Jared Simpson

@jaredtsimpson

Computational Biologist. Principal Investigator at OICR & Assistant Professor .

Se unió en septiembre de 2009

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  1. retwitteó
    4 dic.

    Our preprint introducing >300 Gbp sequencing of microbial community standards is up! Of interest to anyone looking for juicy real data to put tools to the test. Amazing lab work & nice first paper with lab

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  2. retwitteó
    28 nov.

    Now available from : and with colleagues including and measured over 1,000,000,000 Cas9 editing outcomes, and thoroughly dissected the data. 1/

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  3. retwitteó
    28 nov.
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  4. retwitteó
    26 nov.
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  5. retwitteó
    12 nov.

    Announcing a first release of methplotlib: a genome browser for methylation data from nanopolish by . Feedback and contributions more than welcome!

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  6. retwitteó
    23 oct.

    Interested in a long-read assembler with the speed of miniasm and comparable consensus accuracy of canu? Try wtdbg2 by my friend Jue Ruan. A human genome in one day. Also available from bioconda.

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  7. retwitteó
    21 oct.

    TT position available at U of Toronto in genomics and statistical genetics. Great community and colleagues here in Toronto. Potential opportunities for a link with . Please RT

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  8. retwitteó
    18 oct.

    I think this'll be our best promethion run so far! It just blew past 75Gb in 24hours with >2100 pores still sequencing and >96% pore occupancy

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  9. retwitteó
    18 oct.

    Sooo good! Using long-read sequencing to detect imprinted DNA methylation

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  10. retwitteó
    16 oct.

    D-NAscent: dynamics by sequencing reveals on single-molecules replication origins, fork direction & fork pausing. Great collaboration

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  11. 16 oct.

    We just posted a preprint on measuring genome replication by detecting nucleotide analogues incorporated into the yeast genome using signals. Work led by , and .

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  12. retwitteó
    15 oct.

    Never imagined that the malloc in glibc affects the multithreaded performance by this much! :o Impact of malloc on call-methylation performance ...

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  13. 11 sept.

    New nanopolish release (0.10.2) containing the first public version of our poly-A tail length estimator for direct RNA reads: . Developed by Paul Tang in my group.

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  14. retwitteó
    3 ago.

    130.6 Gb from our first PromethION flowcell... The most exciting moment was realising we still had 7000 pores after 64 hours so fuelled it up and kicked it off again!

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  15. 25 jul.

    nanopolish v0.10.1 released: this version changes the interface of the consensus polishing workflow so some pipelines may need to be updated. See the release notes here:

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  16. retwitteó
    24 jul.

    Slides from my talk on "k-mer Data Structures" at :

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  17. retwitteó
    20 jul.

    Received a nice NanoPlot feature suggestion from : evolution of sequencing speed across time. Here is an example of one of our PromethION runs. Available in v1.15.0 from PyPI

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  18. retwitteó
    20 jul.

    Come work with us and help build the foundation for a Canadian approach to national genomics research!

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  19. retwitteó
    8 jul.

    Week end fun : Ecoli consensus and chr22 methylation detection using on my mobile phone for some reads (Includes minimap2 and samtools).

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  20. retwitteó
    5 jul.

    Meet us at : talks on diploid assembly () and on using Strand-seq to sort long reads by chromosome prior to assembly (). Two posters: sequence-to-graph alignment and haplotype phasing. Also, we are LOOKING FOR POSTDOCS.

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