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At first, you will not object
That I am the case, matter and subject

Change my third and I become
Noxious, venomous, even lethal to some

Change my third again then the bars and inns of the city
Are the place where you'll find me, very likely.

What am I?

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up vote 6 down vote accepted

You are a

Topic

At first, you will not object / That I am the case, matter and subject

"Case", "matter", and "subject" are all synonyms for TOPIC.

Change my third and I become / Noxious, venomous, even lethal to some

Change the 3rd letter to X, the word is now TOXIC. As in poisonous.

Change my third again then the bars and inns of the city / Are the place where you'll find me, very likely.

Change the 3rd letter to N, the word is now TONIC. As in gin & tonic water.

As for the title itself

Change the 3rd letter to E. The TOEIC is an English language test.

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ninja'd... :( +1 – Will 3 hours ago
    
^ by 59 secs :D – Techidiot 2 hours ago
1  
What about the title :)? (hint: same trick!) – IAmInPLS 2 hours ago
    
@IAmInPLS Clever, I didn't realize that was a clue. I added it to the answer. – Mike Q 2 hours ago

I think you are -

Topic,Tonic and Toxic

At first, you will not object That I am the case, matter and subject

Topic can be a case, matter or a subject

Change my third and I become Noxious, venomous, even lethal to some

p->x gives Toxic -> Venoumous

Change my third again then the bars and inns of the city Are the place where you'll find me, very likely.

x->n Tonic -> A refresher like an alcohol which serves as a tonic.

Oh well the title:

A test of English for some -> Test -> TOEIC

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This is not it for the title! – IAmInPLS 2 hours ago

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