Lior Pachter

@lpachter

Bren Professor of Computational Biology at Caltech. Blog at .

Pasadena, CA
pachterlab.github.io
Tilmeldt april 2009
217 billeder og videoer Billeder og videoer

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  1. retweetede
    19. dec.

    So why is this result nifty? (1/N)

    The ultra-diffuse galaxy NGC 1052-DF2 with MUSE: I. Kinematics of the stellar body [GA]
    2 svar 22 retweets 62 likes
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  2. retweetede
    for 20 timer siden

    Our Cell Hashing work w/ is out ! Check out a few awesome experimental approaches for scRNA-seq multiplexing: - () - (Gartner Lab) - () -

    1 svar 71 retweets 150 likes
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  3. retweetede
    18. dec.

    With the recent onslaught of posts about the randomness and capricious nature of NIH reviews, I'd like to make a few statements. I agree that the review process is far from optimal, but I do not think it is the random process that many seem to believe:

    2 svar 20 retweets 37 likes
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  4. 18. dec.

    How to write a paper in four minutes

    6 svar 127 retweets 283 likes
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  5. 18. dec.

    An interesting single-cell study of X-inactivation focusing on the identification of escapees via allele-specific expression analysis.

    11 retweets 25 likes
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  6. retweetede
    18. dec.

    Whole blood transcriptome analysis in bipolar disorder reveals strong lithium effect

    7 retweets 15 likes
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  7. retweetede
    15. dec.

    I've always joked that, if my husband and I were hit by a bus, the headline would read "Google Engineer and woman hit by a bus." Except it's not funny because it's true

    Smithsonian names woman to top post at American History Museum
    24 svar 297 retweets 1.213 likes
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  8. retweetede
    10. dec.

    New preprint from our group. Personal favourite from my upcoming thesis.

    6 retweets 9 likes
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  9. 16. dec.

    Design elements reflecting the importance of... chalk. An article on the Roland and Maxine Hall of Mathematics and Physics

    4 retweets 6 likes
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  10. 16. dec.

    This .txt -> .xls -> .m gymnastics is ridiculous but interestingly is more popular as a language for single-cell genomics analysis than C/C++. See , and :

    2 svar 5 retweets 23 likes
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  11. 16. dec.

    Running the demo code for this paper requires (1) downloading a large text file. Then (2) loading it in so it can be saved as a .xls file so that (3) a program provided by the authors can parse the .xls file.

    8 svar 16 retweets 53 likes
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  12. retweetede
    14. dec.

    "goes to show the divide between the way universities market the advancement of women in STEM to the public, compared to the actual experiences of women in these fields." I'm not going to disagree.

    1 svar 2 retweets 6 likes
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  13. retweetede
    14. dec.

    Probably not a good idea to impute single cell RNA-seq data... neuron-specific marker VGlut2/Slc17a6 is expressed at low levels in every single CNS cell cluster after SAVER imputation

    5 svar 15 retweets 41 likes
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  14. 14. dec.

    Interesting paper focusing on extensive splicing dysregulation evident in RNA-seq from post-mortem brains of individuals with psychiatric disorders.

    14 retweets 34 likes
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  15. retweetede
    13. dec.

    Completely missed that our paper came out! TL;DR: Computational efficiency gains from kallisto paired with high concordance to traditional methods = no brainer: use pseudo-alignment/quasi-mapping.

    A comparison of RSEM and kallisto for reproducible cancer RNA-seq analysis with workflow design details by and .
    4 retweets 17 likes
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  16. retweetede
    25. aug. 2015

    “Do the best experiments you can, and always tell the truth. That’s all.” - Sydney Brenner. HT

    16 retweets 21 likes
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  17. retweetede
    11. dec.

    Gene expression during was amazingly stable despite huge changes in the . We tested wheat-rye hybrids, and Ph1 mutants and were surprised how little changed! Great collaboration with

    9 retweets 30 likes
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  18. retweetede
    6. aug.

    Differential gene expression analysis tools exhibit substandard performance for long non-coding RNA-sequencing data

    4 retweets 13 likes
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  19. retweetede
    9. dec.

    Some thoughts on ’s entry in , after being there and chatting with the AlphaFold team and many others: . Warning: long, technical (in parts), and vicious! (but not toward DM :-)

    15 svar 236 retweets 500 likes
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  20. retweetede
    9. dec.

    Rachel Posner, a rabbi's wife, captured this historic image in 1932 in Kiel, Germany, on the 8th night of Chanukah. On the back of the photograph, she wrote: "Death to Judah," so the flag says. "Judah will live forever," so the light answers.

    6 svar 267 retweets 653 likes
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