Tuits

Has blocat @lpachter

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  1. ha retuitat
    19 de des.
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  2. ha retuitat
    fa 20 hores
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  3. ha retuitat
    18 de des.

    With the recent onslaught of posts about the randomness and capricious nature of NIH reviews, I'd like to make a few statements. I agree that the review process is far from optimal, but I do not think it is the random process that many seem to believe:

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  4. 18 de des.
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  5. 18 de des.

    An interesting single-cell study of X-inactivation focusing on the identification of escapees via allele-specific expression analysis.

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  6. ha retuitat
    18 de des.

    Whole blood transcriptome analysis in bipolar disorder reveals strong lithium effect

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  7. ha retuitat
    15 de des.

    I've always joked that, if my husband and I were hit by a bus, the headline would read "Google Engineer and woman hit by a bus." Except it's not funny because it's true

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  8. ha retuitat
    10 de des.

    New preprint from our group. Personal favourite from my upcoming thesis.

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  9. 16 de des.
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  10. 16 de des.

    This .txt -> .xls -> .m gymnastics is ridiculous but interestingly is more popular as a language for single-cell genomics analysis than C/C++. See , and :

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  11. 16 de des.

    Running the demo code for this paper requires (1) downloading a large text file. Then (2) loading it in so it can be saved as a .xls file so that (3) a program provided by the authors can parse the .xls file.

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  12. ha retuitat
    14 de des.

    "goes to show the divide between the way universities market the advancement of women in STEM to the public, compared to the actual experiences of women in these fields." I'm not going to disagree.

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  13. ha retuitat
    14 de des.

    Probably not a good idea to impute single cell RNA-seq data... neuron-specific marker VGlut2/Slc17a6 is expressed at low levels in every single CNS cell cluster after SAVER imputation

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  14. 14 de des.

    Interesting paper focusing on extensive splicing dysregulation evident in RNA-seq from post-mortem brains of individuals with psychiatric disorders.

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  15. ha retuitat
    13 de des.

    Completely missed that our paper came out! TL;DR: Computational efficiency gains from kallisto paired with high concordance to traditional methods = no brainer: use pseudo-alignment/quasi-mapping.

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  16. ha retuitat
    25 d’ag. de 2015

    “Do the best experiments you can, and always tell the truth. That’s all.” - Sydney Brenner. HT

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  17. ha retuitat
    11 de des.

    Gene expression during was amazingly stable despite huge changes in the . We tested wheat-rye hybrids, and Ph1 mutants and were surprised how little changed! Great collaboration with

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  18. ha retuitat
    6 d’ag.

    Differential gene expression analysis tools exhibit substandard performance for long non-coding RNA-sequencing data

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  19. ha retuitat
    9 de des.

    Some thoughts on ’s entry in , after being there and chatting with the AlphaFold team and many others: . Warning: long, technical (in parts), and vicious! (but not toward DM :-)

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  20. ha retuitat
    9 de des.

    Rachel Posner, a rabbi's wife, captured this historic image in 1932 in Kiel, Germany, on the 8th night of Chanukah. On the back of the photograph, she wrote: "Death to Judah," so the flag says. "Judah will live forever," so the light answers.

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