Lior Pachter

@lpachter

Bren Professor of Computational Biology at Caltech. Blog at .

Pasadena, CA
pachterlab.github.io
Připojil se duben 2009
217 fotek nebo videí Fotky a videa

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  1. Retweetnuto uživatelem
    19. 12.

    So why is this result nifty? (1/N)

    The ultra-diffuse galaxy NGC 1052-DF2 with MUSE: I. Kinematics of the stellar body [GA]
    22 retweetů 62lajků
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  2. Retweetnuto uživatelem
    před 20 hodinami

    Our Cell Hashing work w/ is out ! Check out a few awesome experimental approaches for scRNA-seq multiplexing: - () - (Gartner Lab) - () -

    1 reply 71 retweetů 151lajků
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  3. Retweetnuto uživatelem
    18. 12.

    With the recent onslaught of posts about the randomness and capricious nature of NIH reviews, I'd like to make a few statements. I agree that the review process is far from optimal, but I do not think it is the random process that many seem to believe:

    20 retweetů 37lajků
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  4. 18. 12.

    How to write a paper in four minutes

    6 replies 127 retweetů 283lajků
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  5. 18. 12.

    An interesting single-cell study of X-inactivation focusing on the identification of escapees via allele-specific expression analysis.

    11 retweetů 25lajků
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  6. Retweetnuto uživatelem
    18. 12.

    Whole blood transcriptome analysis in bipolar disorder reveals strong lithium effect

    7 retweetů 15lajků
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  7. Retweetnuto uživatelem
    15. 12.

    I've always joked that, if my husband and I were hit by a bus, the headline would read "Google Engineer and woman hit by a bus." Except it's not funny because it's true

    Smithsonian names woman to top post at American History Museum
    24 replies 297 retweetů 1 213lajků
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  8. Retweetnuto uživatelem
    10. 12.

    New preprint from our group. Personal favourite from my upcoming thesis.

    6 retweetů 9lajků
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  9. 16. 12.

    Design elements reflecting the importance of... chalk. An article on the Roland and Maxine Hall of Mathematics and Physics

    4 retweety 6lajků
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  10. 16. 12.

    This .txt -> .xls -> .m gymnastics is ridiculous but interestingly is more popular as a language for single-cell genomics analysis than C/C++. See , and :

    5 retweetů 23lajků
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  11. 16. 12.

    Running the demo code for this paper requires (1) downloading a large text file. Then (2) loading it in so it can be saved as a .xls file so that (3) a program provided by the authors can parse the .xls file.

    8 replies 16 retweetů 53lajků
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  12. Retweetnuto uživatelem
    14. 12.

    "goes to show the divide between the way universities market the advancement of women in STEM to the public, compared to the actual experiences of women in these fields." I'm not going to disagree.

    1 reply 2 retweety 6lajků
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  13. Retweetnuto uživatelem
    14. 12.

    Probably not a good idea to impute single cell RNA-seq data... neuron-specific marker VGlut2/Slc17a6 is expressed at low levels in every single CNS cell cluster after SAVER imputation

    5 replies 15 retweetů 41lajků
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  14. 14. 12.

    Interesting paper focusing on extensive splicing dysregulation evident in RNA-seq from post-mortem brains of individuals with psychiatric disorders.

    14 retweetů 34lajků
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  15. Retweetnuto uživatelem
    13. 12.

    Completely missed that our paper came out! TL;DR: Computational efficiency gains from kallisto paired with high concordance to traditional methods = no brainer: use pseudo-alignment/quasi-mapping.

    A comparison of RSEM and kallisto for reproducible cancer RNA-seq analysis with workflow design details by and .
    4 retweety 17lajků
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  16. Retweetnuto uživatelem
    25. 8. 2015

    “Do the best experiments you can, and always tell the truth. That’s all.” - Sydney Brenner. HT

    16 retweetů 21lajků
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  17. Retweetnuto uživatelem
    11. 12.

    Gene expression during was amazingly stable despite huge changes in the . We tested wheat-rye hybrids, and Ph1 mutants and were surprised how little changed! Great collaboration with

    9 retweetů 30lajků
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  18. Retweetnuto uživatelem
    6. 8.

    Differential gene expression analysis tools exhibit substandard performance for long non-coding RNA-sequencing data

    4 retweety 13lajků
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  19. Retweetnuto uživatelem
    9. 12.

    Some thoughts on ’s entry in , after being there and chatting with the AlphaFold team and many others: . Warning: long, technical (in parts), and vicious! (but not toward DM :-)

    15 replies 236 retweetů 500lajků
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  20. Retweetnuto uživatelem
    9. 12.

    Rachel Posner, a rabbi's wife, captured this historic image in 1932 in Kiel, Germany, on the 8th night of Chanukah. On the back of the photograph, she wrote: "Death to Judah," so the flag says. "Judah will live forever," so the light answers.

    6 replies 267 retweetů 653lajků
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