

Ryo Kanada, Ryota Shinagawa, and Kazuo Sasaki
Phys. Rev. E 98, 062110 (2018)
This paper presents a description of the dynamics of a molecular motor as a Brownian particle diffusing through a set of potential wells. The authors identify two characteristic time scales: a residence time in a well and a stepping time between wells. They observe an enhancement of diffusion when these two times are comparable and propose that this could be an explanation for a similar phenomenon recently observed experimentally.

Pierre A. Haas and Raymond E. Goldstein
Phys. Rev. E 98, 052415 (2018)
Some organisms finalize their embryonic development by inverting themselves, and this paper presents an elastic theory to explain the inversion mechanism. The authors analyze a particular scheme in which four lips peel back progressively to flip the embryo inside out. This framework successfully reproduces a number of experimental observations and sets the stage for a discussion of circumstances when the inversion is hindered.

Manon Benedito and Stefano Giordano
Phys. Rev. E 98, 052146 (2018)
This paper studies the mechanical properties of a chain of bistable elements that interact with each other, such as a molecular chain of folding and unfolding units. The authors observe that for a small number of elements the thermodynamic limit is not reached, and the behavior depends on the boundary conditions. The results are compared to experimental observations in stretching biological systems.

Philip Greulich and Benjamin D. Simons
Phys. Rev. E 98, 050401(R) (2018)
Motivated by the process of tumor initiation, the authors study extreme value statistics of mutations in a model of a renewing cell population. They combine the genealogy of the cell population with the theory of branching random walks and estimate the age-dependent probability for the number of mutations in a cell to exceed a threshold value.


Matthew Garrod and Nick S. Jones
Phys. Rev. E 98, 052316 (2018)

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