To be EXTREMELY intoxicated from the use of alcohol or drugs. See stoned, high, enke, drunk.

To be very intoxicated from the use of alcohol or drugs.

To bring to a specific state by drinking alcoholic liquors, or other drugs.

To run out of health on Grand theft auto.

Also, to have a large amount of poisonous chemicals in your sytem.
You can not be WASTED if you only have marijuana in your system, because marijuana does not consist of the lethal toxins that other drugs contain.

The act of drinking a shitload of alcholic beverages to the point of no longer being able to stand.

Or

The act of getting the fuck shot out of you by Gangsters.

to drink alcohol to the point of being heavly intoxicated... drunk

Verb(pased)

1- Drunk or otherwise intoxicated off your ass

2- The act of obliterating something or someone in a computer/video game, not always online.