Release notes

Latest release note

v.66
InterPro 66.0
23rd November 2017

Features include:

  • The addition of 285 InterPro entries.
  • An update to PROSITE patterns (2017_09), HAMAP (2017_10) and PROSITE profiles (2017_09).
  • Integration of 1031 new methods from the CDD (140), Pfam (3), PROSITE profiles (22), PANTHER (806), HAMAP (58) and ProDom (2) databases.

Previous release notes

Contents and coverage of InterPro 66.0

InterPro protein matches are now calculated for all UniProtKB and UniParc proteins. The following statistics are for all UniProtKB proteins.
InterPro release 66.0 contains 32568 entries (last entry: IPR037597), representing:

InterPro cites 54049 publications in PubMed.

Member database information

Signature database Version Signatures* Integrated signatures**
CATH-Gene3D 4.1.0 2737 1366
CDD 3.16 12805 2535
HAMAP 2017_10 2216 2216
PANTHER 12.0 90742 7387
Pfam 31.0 16712 16109
PIRSF 3.02 3285 3223
PRINTS 42.0 2106 1974
ProDom 2006.1 1894 1307
PROSITE patterns 2017_09 1309 1289
PROSITE profiles 2017_09 1194 1161
SFLD 3 303 143
SMART 7.1 1312 1263
SUPERFAMILY 1.75 2019 1595
TIGRFAMs 15.0 4488 4445

* Some signatures may not have matches to UniProtKB proteins.
** Not all signatures of a member database may be integrated at the time of an InterPro release
We use MobiDB-lite, a derivative of the MobiDB database, to provide consensus annotation of long-range intrinsic disorder in protein sequences. Read more about MobiDB-lite in Bioinformatics, 33(9), 2017, 1402–1404, (doi: 10.1093/bioinformatics/btx015).

Sequence database Version Count Count of proteins matching
any signature integrated signatures
UniProtKB2017_119926141687660626 (88.3%)80362872 (81.0%)
UniProtKB/TrEMBL2017_119870522087116114 (88.3%)79825500 (80.9%)
UniProtKB/Swiss-Prot2017_11556196544512 (97.9%)537372 (96.6%)

InterPro2GO

Total number of GO terms mapped to InterPro entries - 33703

List of InterPro2GO mappings. These are also available through the EBI GO browser QuickGO