To coincide with the 200th anniversary of the publication of An Essay on the Shaking Palsy by James Parkinson, Goedert and Compston explore the origins of the eponym 'Parkinson's disease'. Although Jean-Martin Charcot is often credited with introducing the name in the 1880s, it can actually be traced back to an 1865 publication by William Rutherford Sanders.

An analysis of biotech and pharma stock prices since 1930 reveals sharp differences in the risk-adjusted returns of the two sectors.

Hydropower is critical to eastern and southern Africa but it is at risk from climate variability. Conway et al. examine river basins and rainfall variability to explore potential hydropower disruption for present and planned generation sites, highlighting the risks to supply and their spatial interlinkages.

All energy generation technologies emit greenhouse gases during their life cycle as a result of construction and operation. Pehl et al. integrate life-cycle assessment and energy modelling to analyse the emissions contributions of different technologies across their lifespan in future low-carbon power systems.

Models show that several aspects of Earth’s top-of-atmosphere energy budget and the magnitude of projected global warming are correlated, enabling us to infer that future warming has been underestimated.