DUBLIN – The fundraising momentum the European biopharmaceutical sector developed in the final week of September continued into the early weeks of the fourth quarter, with substantial levels of private and public investment activity in evidence across multiple geographies and markets.

An FDA advisory committee made history Thursday with its unconditional support for Spark Therapeutics Inc.’s Luxturna, which is on track to become the first gene therapy to be approved in the U.S. to treat an inherited disease.

"What we've accomplished from then to now is what we dreamt of," Ardelyx Inc. CEO Mike Raab told BioWorld, referring to stellar phase III data with Na-hydrogen exchanger 3 (NHE3) transporter blocker tenapanor in irritable bowel syndrome (IBS-C), unveiled less than a week before the 10-year anniversary of the firm's founding. more »

Claude-Henry Volmar is no longer particularly surprised when clinical trials of drugs for Alzheimer's disease (AD) fail. And fail they do, basically without fail.

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The amount of cash generated by global public and private biopharmaceutical companies was up significantly in the third quarter compared to the second quarter. The almost $16 billion haul was 45 percent higher than the $11 billion raised during the second quarter and almost 25 percent higher than the total generated in the same period last year. Thanks to their higher company valuations, public companies were able to conduct public offerings with confidence, and the amount of private capital raised ballooned to more than $3.23 billion – a 61 percent increase over the $2 billion generated in the second quarter of this year.
One of the challenges for weight loss is that the body is evolutionarily programmed to worry about famines, not feasts. As a result, losing weight, if not exactly easy, is achievable for many individuals. Keeping that weight off, though, is a formidable challenge, because weight loss sets off powerful compensatory mechanisms in the body. (See BioWorld, Sept. 26, 2017.)
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