Nils Homer

@nilshomer

I write software for Biologists. Consultant, Bioinformatician, Computer Scientist, Coder, Father of 2xGirls. Opinions are my own.

ಜುಲೈ 2009 ಸಮಯದಲ್ಲಿ ಸೇರಿದ್ದಾರೆ

ಟ್ವೀಟ್‌ಗಳು

ನೀವು @nilshomer ಅವರನ್ನು ತಡೆಹಿಡಿದಿರುವಿರಿ

ಈ ಟ್ವೀಟ್‌ಗಳನ್ನು ವೀಕ್ಷಿಸಲು ನೀವು ಖಚಿತವಾಗಿ ಬಯಸುವಿರಾ? ಟ್ವೀಟ್ ವೀಕ್ಷಣೆಯು @nilshomer ಅವರ ತಡೆತೆರವುಗೊಳಿಸುವುದಿಲ್ಲ

  1. 5 ಗಂಟೆಗಳ ಹಿಂದೆ
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  2. ಡಿಸೆಂ 18

    Update: authors gave me access to their software.

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  3. ಡಿಸೆಂ 17

    My children are the world's most successful people, followed by their parents 15 minutes later.

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  4. ಡಿಸೆಂ 16

    These tweets are not meant to anonymize the paper or the authors. They should feel bad.

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  5. ಡಿಸೆಂ 16

    How many weeks should I wait until I reach out to the editors? They’re “cleaning up the code to make it more reasonable”. That should have been handled in review when the reviewers ran their code.

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  6. ಡಿಸೆಂ 16

    “Further information and requests for resources, including computer code implementing the mathematical formulas used in this study, should be directed to and will be fulfilled by the lead contact”. ~ Nature/Science/Cell paper. Narrator: “it wasn’t”

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  7. ಡಿಸೆಂ 15

    I can only think of the history of French Horn players.

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  8. ಡಿಸೆಂ 12
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  9. ಡಿಸೆಂ 11

    regex_error

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  10. ಡಿಸೆಂ 11

    I think a better question is how many workflow framework/languages/tools do you use on a regular basis? The legends know that there is no one to rule them all. A follow up would be how many have you written?

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  11. ಅವರು ಮರುಟ್ವೀಟಿಸಿದ್ದಾರೆ
    ಡಿಸೆಂ 9
    ಅವರಿಗೆ ಪ್ರತಿಕ್ರಿಯಿಸುತ್ತಿದ್ದಾರೆ

    Amen. One of the hard (and expensive) lessons we’ve learned on 50k+ scale exome cohorts is that joint calling does not always improve the call set, and sometimes it can make it significantly worse. The details matter a lot, and even comparing large-scale call sets is nontrivial.

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  12. ಅವರು ಮರುಟ್ವೀಟಿಸಿದ್ದಾರೆ
    ಡಿಸೆಂ 5

    I am formally looking for a few postdocs who would like to work with me on developing advanced computational algorithms. Please see the job listing for details.

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  13. ಡಿಸೆಂ 5

    I am happy to pay <$75 for thumb drive with my raw data (thanks ), but $499 for raw data from is ridiculous. I could get half a whole genome done on for that. So much for contributing Helix data to . </rant>

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  14. ಅವರು ಮರುಟ್ವೀಟಿಸಿದ್ದಾರೆ
    ಡಿಸೆಂ 4

    A brand new app just out! helps you create a list of candidate genes corresponding to the patient's disease and phenotype, using commercially available panel tests. Details at: .

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  15. ಅವರು ಮರುಟ್ವೀಟಿಸಿದ್ದಾರೆ
    ಡಿಸೆಂ 3

    It cannot be overstated how important it is to account for proximal variants when predicting neoantigens from genome & transcriptome data for personalized cancer vaccines and other immunotherapies. Glad to see this paper coming from and ’s groups.

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  16. ಡಿಸೆಂ 3

    I am going to need a bigger bwa. [bwa_aln_core] calculate SA coordinate... 26473.65 sec [bwa_aln_core] convert to sequence coordinate... 58.33 sec [bwa_aln_core] refine gapped alignments... 7.84 sec [bwa_aln_core] 7602176 sequences have been processed.

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  17. ಡಿಸೆಂ 2

    I may have gone a little overboard with DTC genetic testing. I already have 23andMe on their old array and their exome, as well as PGP Complete Genomics. I am one step closer to a gold standard genome. Who am I missing?

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  18. ನವೆಂ 30

    Now, back to the discussion. Of course she can go back to school. This really tough for mid-career professionals. Especially those with burgeoning families. Is industry a better option? How does she get the break she needs? How can I help?

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  19. ನವೆಂ 30

    “...There are not many open source projects for these languages, so my experience is minimal aside from my own courses/side projects.” 5/n

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  20. ನವೆಂ 30

    “...My undergraduate degree had a plant genomics focus ... and I had only taken one Bioinformatics class. Right now I'm shadowing a group of people that use R for genomics research, however I do not have direct experience myself...” 4/n

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