Peter Kraft

@GENES_PK

Professor, Harvard T.H. Chan School of Public Health - Director, Program in Genetic Epidemiology and Statistical Genetics

ಜೂನ್ 2013 ಸಮಯದಲ್ಲಿ ಸೇರಿದ್ದಾರೆ

ಟ್ವೀಟ್‌ಗಳು

ನೀವು @GENES_PK ಅವರನ್ನು ತಡೆಹಿಡಿದಿರುವಿರಿ

ಈ ಟ್ವೀಟ್‌ಗಳನ್ನು ವೀಕ್ಷಿಸಲು ನೀವು ಖಚಿತವಾಗಿ ಬಯಸುವಿರಾ? ಟ್ವೀಟ್ ವೀಕ್ಷಣೆಯು @GENES_PK ಅವರ ತಡೆತೆರವುಗೊಳಿಸುವುದಿಲ್ಲ

  1. ಪಿನ್ ಮಾಡಿದ ಟ್ವೀಟ್
    ಅಕ್ಟೋ 25

    Summary statistics from the latest & greatest GWAS of breast, ovarian, and prostate cancer available here: If you know of publicly available summary stats for other cancers, please let me know!

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  2. ಅವರು ಮರುಟ್ವೀಟಿಸಿದ್ದಾರೆ
    ಡಿಸೆಂ 18

    If you're not a fan of extreme p-values in you can stop reading right here. But since I've been following the Manhattan plots generated by from the group I thought I'd "skip to the end" and look up most extreme p-value for any trait/any SNP 👇

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  3. ಅವರು ಮರುಟ್ವೀಟಿಸಿದ್ದಾರೆ
    ಡಿಸೆಂ 17

    Our recent study of experiences of members of in identifying secondary / "incidental" findings in whole genome data. Deserves careful consideration when developing

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  4. ಅವರು ಮರುಟ್ವೀಟಿಸಿದ್ದಾರೆ
    ಡಿಸೆಂ 14

    1/n This paper has been many years in the making both conceptually and in terms of the time to generate the data. It has been part of almost all my scientific life (or at least since I started my PhD). I thought I'd write the timeline down.

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  5. ಅವರು ಮರುಟ್ವೀಟಿಸಿದ್ದಾರೆ
    ಡಿಸೆಂ 13
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  6. ಡಿಸೆಂ 14

    BIG IMPORTANT CAVEAT: these scores were developed and validated in European-ancestry women. Similar prediction accuracy should be achievable in other groups, but will take larger population-specific studies to realize.

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  7. ಡಿಸೆಂ 14

    Identifying women in the general population with 3-4x risks of breast cancer: definitely warrants a closer look at clinical utility and implementation challenges. Looking is happening, so watch this space.

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  8. ಡಿಸೆಂ 14

    By using individual data, authors were able to prune using conditional regression analyses, rather than pairwise r2 values, as typically done in “prune and threshold” analyses. They also performed regularized regression (lasso).

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  9. ಡಿಸೆಂ 14

    The scores had good calibration on the odds ratio scale—both overall and in the tails—in 20,000 independent cases and controls.

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  10. ಡಿಸೆಂ 14

    Polygenic risk scores for breast cancer and estrogen-receptor subtypes, developed using individual-level data on 170,000 cases and controls from the Breast Cancer Association Consortium. 313 SNPs can identify 1% of women at 4.3-fold increased risk of ER+ disease.

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  11. ಡಿಸೆಂ 13

    For those who couldn't see this in person, the preprint from et al: "Hidden 'risk' in polygenic scores: clinical use today could exacerbate health disparities"

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  12. ಅವರು ಮರುಟ್ವೀಟಿಸಿದ್ದಾರೆ
    ಡಿಸೆಂ 12

    We are seeing a positive trend in authors sharing summary statistics, with many authors/consortia (thanks , MAGIC) now contacting us and asking us to host. We're working hard on increasing this and welcome more community engagement!

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  13. ಡಿಸೆಂ 6

    Inspired by granting agency who told us—after panicked furious round of editing—just to ignore the 70 character title limit on application form. Oh, and Kafka.

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  14. ಡಿಸೆಂ 6

    BEFORE THE LAW (revised) Guy walks up to the door to the law, asks the guard, “Can I get in?” “NO!” “Please?” “Aw, sure, dude, go on in, I was just f-in with you.” THE END

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  15. ಡಿಸೆಂ 6

    A whole uninterrupted morning doing and talking about science did wonders for my mood. Treating myself to lunch... reenergized to put out some admin brush fires.

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  16. ಅವರು ಮರುಟ್ವೀಟಿಸಿದ್ದಾರೆ
    ಡಿಸೆಂ 6

    If you know anyone in undergrad studying a science-related major, please encourage them to apply to our summer pipeline program at Harvard (). This program is geared towards minorities and includes housing and a stipend!

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  17. ಅವರು ಮರುಟ್ವೀಟಿಸಿದ್ದಾರೆ
    ಡಿಸೆಂ 6

    I've compiled a list of tips that I find very useful when making presentations. All of these suggestions are from my lab, peers, and others who were nice enough to offer their feedback!

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  18. ಡಿಸೆಂ 6

    Does anybody know of empirical studies of burnout among lawyers? I found two articles on judge stress in "Psychiatry, Psychology and Law" and one on law students, but nothing on lawyers.

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  19. ಅವರು ಮರುಟ್ವೀಟಿಸಿದ್ದಾರೆ
    ಡಿಸೆಂ 5

    Postdoc position available in my group at Univ of Chicago. Work at the intersection of genetic, molecular, & environmental epidemiology. With a focus on biological aging and cancer. Pls pass along or get in touch!

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  20. ಅವರು ಮರುಟ್ವೀಟಿಸಿದ್ದಾರೆ
    ಡಿಸೆಂ 3

    Thanks to for the opportunity to chat about the CRISPR babies & that crazy interview w/ . Nice list of the biggest problems - and you know it's bad when, in today's age of bite-size news, you end up with 15 items and 3000 words!

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  21. ಅವರು ಮರುಟ್ವೀಟಿಸಿದ್ದಾರೆ
    ನವೆಂ 29

    Retrospective Research Ethics for Dummies: 1.Unethical acts should be met with "balanced" responses 2.Condemnation of unethical acts is bullying 3.Informed consent & research protocols = paperwork & checklists 4.If nothing goes wrong, unethical actions are okay ...1/3

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ಲೋಡಿಂಗ್ ಸಮಯ ಸ್ವಲ್ಪ ತೆಗೆದುಕೊಳ್ಳುತ್ತಿರುವಂತೆನಿಸುತ್ತದೆ.

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