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Title:
Genomic Comparison of the Ants Camponotus floridanus and Harpegnathos saltator
Authors:
Bonasio, Roberto; Zhang, Guojie; Ye, Chaoyang; Mutti, Navdeep S.; Fang, Xiaodong; Qin, Nan; Donahue, Greg; Yang, Pengcheng; Li, Qiye; Li, Cai; Zhang, Pei; Huang, Zhiyong; Berger, Shelley L.; Reinberg, Danny; Wang, Jun; Liebig, Jürgen
Affiliation:
AA(Department of Biochemistry, New York University School of Medicine, 522 First Avenue, New York, NY 10016, USA.), AB(Chinese Academy of Sciences--Max Planck Junior Research Group, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China.; Beijing Genomics Institute--Shenzhen, Shenzhen 518083, China.), AC(Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.), AD(School of Life Sciences, Arizona State University, Tempe, AZ 85287, USA.), AE(Beijing Genomics Institute--Shenzhen, Shenzhen 518083, China.), AF(Beijing Genomics Institute--Shenzhen, Shenzhen 518083, China.), AG(Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.), AH(Beijing Genomics Institute--Shenzhen, Shenzhen 518083, China.), AI(Beijing Genomics Institute--Shenzhen, Shenzhen 518083, China.), AJ(Beijing Genomics Institute--Shenzhen, Shenzhen 518083, China.), AK(Beijing Genomics Institute--Shenzhen, Shenzhen 518083, China.), AL(Beijing Genomics Institute--Shenzhen, Shenzhen 518083, China.), AM(Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.), AN(Department of Biochemistry, New York University School of Medicine, 522 First Avenue, New York, NY 10016, USA.; Howard Hughes Medical Institute, New York University Medical School, New York, NY 10016, USA.), AO(Beijing Genomics Institute--Shenzhen, Shenzhen 518083, China.; Department of Biology, University of Copenhagen, Copenhagen DK-2200, Denmark.), AP(School of Life Sciences, Arizona State University, Tempe, AZ 85287, USA.)
Publication:
Science, Volume 329, Issue 5995, pp. 1068- (2010). (Sci Homepage)
Publication Date:
08/2010
Category:
GENETICS
Origin:
SCIENCE
Abstract Copyright:
(c) 2010: Science
DOI:
10.1126/science.1192428
Bibliographic Code:
2010Sci...329.1068B

Abstract

The organized societies of ants include short-lived worker castes displaying specialized behavior and morphology and long-lived queens dedicated to reproduction. We sequenced and compared the genomes of two socially divergent ant species: Camponotus floridanus and Harpegnathos saltator. Both genomes contained high amounts of CpG, despite the presence of DNA methylation, which in non-Hymenoptera correlates with CpG depletion. Comparison of gene expression in different castes identified up-regulation of telomerase and sirtuin deacetylases in longer-lived H. saltator reproductives, caste-specific expression of microRNAs and SMYD histone methyltransferases, and differential regulation of genes implicated in neuronal function and chemical communication. Our findings provide clues on the molecular differences between castes in these two ants and establish a new experimental model to study epigenetics in aging and behavior.
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