Truncations to PD-L1's 3' untranslated region were detected in a variety of tumor types, apparently increasing expression of the gene and decreasing immune response to it.
The recruitment of Rick Wilson and Elaine Mardis from Washington University in St. Louis was made possible by a new $10 million gift from the Nationwide Foundation.
Noridian proposes to cover several biomarker tests for guiding chemotherapy decisions for breast cancer patients with node-negative disease but not when it's node positive.
The Buffalo, NY-based firm will use the proceeds to grow its marketing, automation, and operations, and to launch additional molecular diagnostic products.
Four patients still want the government to investigate their allegations against Myriad, even though the firm complied with their data request at the last hour.
A genome-wide association study involving nearly 6,000 individuals identified variants linked to nose-related features and chin protrusion in Latin Americans.
A study in NEJM found that rare, loss-of-function mutations in the asialoglycoprotein receptor gene coincide with lower non-HDL levels and decreased coronary artery disease risk.