Elke Muhlberger, PhD
Professor
Boston University Chobanian & Avedisian School of Medicine
Dept of Microbiology

PhD, Philipps-Universität Marburg
MA, Philipps-Universität Marburg



Virologist;
Expert in molecular biology of Marburg and Ebola viruses and other highly pathogenic viruses;
Experienced in BSL4 work;
Focus on virus-host interaction.

Faculty
Boston University
National Emerging Infectious Disease Lab


Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences


Member
Boston University
Genome Science Institute




National Emerging Infectious Diseases Laboratories Operations
07/08/2021 - 06/30/2026 (Key Person)
PI: Ronald B. Corley, PhD
NIH/National Institute of Allergy & Infectious Diseases
2UC7AI095321-08

Uncovering the RNA regulatory Mechanisms driving pathogenicity at mass-caualty viruses: Merging the technologies of RNA biology and enhanced biosafety to create the next generation of broad spectrum,
10/01/2022 - 09/30/2025 (Multi-PI)
PI: Elke Muhlberger, PhD
Howard Hughes Medical Institute


Uncovering the RNA regulatory mechanisms driving pathogenicity of mass-casualty viruses: Merging the technologies of RNA biology and enhanced biosafety to create the next generation of broad spectrum
10/01/2022 - 09/30/2025 (Multi-PI)
PI: Elke Muhlberger, PhD
Howard Hughes Medical Institute


Uncovering the RNA regulatory mechanisms driving pathogenicity of mass-casualty viruses: Merging the technologies of RNA biology and enhanced biosafety to create the next generation of broad spectrum,
10/01/2022 - 09/30/2025 (PI)
Howard Hughes Medical Institute


Reverse genetic tools and novel models of henipavirus infection
09/28/2022 - 09/30/2025 (PI)
Bill and Melinda Gates Foundation


Dissecting the mechanisms of intestinal epithelial injury by Ebola Virus using iPSC-derived intestinal organoids
07/05/2022 - 06/30/2024 (Subcontract PI)
Boston Medical Center Corporation NIH NIAID
1R21AI167369-01A1

Elucidating the immune response of Schreiber's bats to Lloviu virus infection in vitro and in vivo
02/24/2022 - 01/31/2024 (PI)
NIH/National Institute of Allergy & Infectious Diseases
1R21AI169646-01

Mechanisms of Marburg virus gene expression
05/08/2018 - 04/30/2023 (Multi-PI)
PI: Elke Muhlberger, PhD
NIH/National Institute of Allergy & Infectious Diseases
5R01AI133486-05

Thwarting Influenza with RNA-powered Modulators (ThIRM)
03/01/2022 - 03/31/2023 (Subcontract PI)
Georgia Institute of Technology DOD DARPA


COVID Fast Grants
05/01/2020 - 02/28/2023 (PI)
Emergent Ventures at the Mercatus Center, George Mason University


Showing 10 of 27 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2022 Dissecting the mechanisms of intestinal epithelial injury by Ebola virus using iPSC-derived intestinal organoids 1R21AI167369-01A1
2022 Elucidating the immune response of Schreiber's bats to Lloviu virus infection in vitro and in vivo 1R21AI169646-01
2022 Mechanisms of Marburg virus gene expression 5R01AI133486-05
2021 Mechanisms of Marburg virus gene expression 5R01AI133486-04 3
2020 Deep characterization of the biogenesis and function of Ebola virus microRNAs 5R21AI147285-02
2020 Mechanisms of Marburg virus gene expression 5R01AI133486-03 3
2020 Integrated Support Services Core 5UC7AI095321-07-8669 1
2019 Deep characterization of the biogenesis and function of Ebola virus microRNAs 1R21AI147285-01
2019 The role of TLR4 signaling in the pathogenesis of filovirus infection 5R21AI135912-02 2
2019 Mechanisms of Marburg virus gene expression 5R01AI133486-02 3
Showing 10 of 29 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Hume AJ, Heiden B, Olejnik J, Suder EL, Ross S, Scoon WA, Bullitt E, Ericsson M, White MR, Turcinovic J, Thao TTN, Hekman RM, Kaserman JE, Huang J, Alysandratos KD, Toth GE, Jakab F, Kotton DN, Wilson AA, Emili A, Thiel V, Connor JH, Kemenesi G, Cifuentes D, Mühlberger E. Correction: Recombinant Lloviu virus as a tool to study viral replication and host responses. PLoS Pathog. 2022 Jun; 18(6):e1010659.View Related Profiles. PMID: 35749346; PMCID: PMC9231773; DOI: 10.1371/journal.ppat.1010659;
     
  2. Cressey TN, Shareef AM, Kleiner VA, Noton SL, Byrne PO, McLellan JS, Mühlberger E, Fearns R. Distinctive features of the respiratory syncytial virus priming loop compared to other non-segmented negative strand RNA viruses. PLoS Pathog. 2022 06; 18(6):e1010451.View Related Profiles. PMID: 35731802; PMCID: PMC9255747; DOI: 10.1371/journal.ppat.1010451;
     
  3. Kemenesi G, Tóth GE, Mayora-Neto M, Scott S, Temperton N, Wright E, Mühlberger E, Hume AJ, Suder EL, Zana B, Boldogh SA, Görföl T, Estók P, Lanszki Z, Somogyi BA, Nagy Á, Pereszlényi CI, Dudás G, Földes F, Kurucz K, Madai M, Zeghbib S, Maes P, Vanmechelen B, Jakab F. Isolation of infectious Lloviu virus from Schreiber's bats in Hungary. Nat Commun. 2022 Mar 31; 13(1):1706.View Related Profiles. PMID: 35361761; PMCID: PMC8971391; DOI: 10.1038/s41467-022-29298-1;
     
  4. Jalloh S, Olejnik J, Berrigan J, Nisa A, Suder EL, Akiyama H, Lei M, Tyagi S, Bushkin Y, Mühlberger E, Gummuluru S. CD169-mediated restrictive SARS-CoV-2 infection of macrophages induces pro-inflammatory responses. bioRxiv. 2022 Mar 30.View Related Profiles. PMID: 35378756; PMCID: PMC8978933; DOI: 10.1101/2022.03.29.486190;
     
  5. Miorin L, Mire CE, Ranjbar S, Hume AJ, Huang J, Crossland NA, White KM, Laporte M, Kehrer T, Haridas V, Moreno E, Nambu A, Jangra S, Cupic A, Dejosez M, Abo KA, Tseng AE, Werder RB, Rathnasinghe R, Mutetwa T, Ramos I, de Aja JS, de Alba Rivas CG, Schotsaert M, Corley RB, Falvo JV, Fernandez-Sesma A, Kim C, Rossignol JF, Wilson AA, Zwaka T, Kotton DN, Mühlberger E, García-Sastre A, Goldfeld AE. The oral drug nitazoxanide restricts SARS-CoV-2 infection and attenuates disease pathogenesis in Syrian hamsters. bioRxiv. 2022 Feb 09.View Related Profiles. PMID: 35169796; PMCID: PMC8845418; DOI: 10.1101/2022.02.08.479634;
     
  6. Amraei R, Xia C, Olejnik J, White MR, Napoleon MA, Lotfollahzadeh S, Hauser BM, Schmidt AG, Chitalia V, Mühlberger E, Costello CE, Rahimi N. Extracellular vimentin is an attachment factor that facilitates SARS-CoV-2 entry into human endothelial cells. Proc Natl Acad Sci U S A. 2022 02 08; 119(6).View Related Profiles. PMID: 35078919; PMCID: PMC8833221; DOI: 10.1073/pnas.2113874119;
     
  7. Hume AJ, Heiden B, Olejnik J, Suder EL, Ross S, Scoon WA, Bullitt E, Ericsson M, White MR, Turcinovic J, Thao TTN, Hekman RM, Kaserman JE, Huang J, Alysandratos KD, Toth GE, Jakab F, Kotton DN, Wilson AA, Emili A, Thiel V, Connor JH, Kemenesi G, Cifuentes D, Mühlberger E. Recombinant Lloviu virus as a tool to study viral replication and host responses. PLoS Pathog. 2022 02; 18(2):e1010268.View Related Profiles. PMID: 35120176; PMCID: PMC8849519; DOI: 10.1371/journal.ppat.1010268;
     
  8. Wang R, Hume AJ, Beermann ML, Simone-Roach C, Lindstrom-Vautrin J, Le Suer J, Huang J, Olejnik J, Villacorta-Martin C, Bullitt E, Hinds A, Ghaedi M, Rollins S, Werder RB, Abo KM, Wilson AA, Mühlberger E, Kotton DN, Hawkins FJ. Human airway lineages derived from pluripotent stem cells reveal the epithelial responses to SARS-CoV-2 infection. Am J Physiol Lung Cell Mol Physiol. 2022 03 01; 322(3):L462-L478.View Related Profiles. PMID: 35020534; PMCID: PMC8917936; DOI: 10.1152/ajplung.00397.2021;
     
  9. Leon J, Michelson DA, Olejnik J, Chowdhary K, Oh HS, Hume AJ, Galván-Peña S, Zhu Y, Chen F, Vijaykumar B, Yang L, Crestani E, Yonker LM, Knipe DM, Mühlberger E, Benoist C. A virus-specific monocyte inflammatory phenotype is induced by SARS-CoV-2 at the immune-epithelial interface. Proc Natl Acad Sci U S A. 2022 01 04; 119(1).View Related Profiles. PMID: 34969849; PMCID: PMC8740714; DOI: 10.1073/pnas.2116853118;
     
  10. Kuhn JH, Adkins S, Agwanda BR, Al Kubrusli R, Alkhovsky SV, Amarasinghe GK, Avšic-Županc T, Ayllón MA, Bahl J, Balkema-Buschmann A, Ballinger MJ, Basler CF, Bavari S, Beer M, Bejerman N, Bennett AJ, Bente DA, Bergeron É, Bird BH, Blair CD, Blasdell KR, Blystad DR, Bojko J, Borth WB, Bradfute S, Breyta R, Briese T, Brown PA, Brown JK, Buchholz UJ, Buchmeier MJ, Bukreyev A, Burt F, Büttner C, Calisher CH, Cao M, Casas I, Chandran K, Charrel RN, Cheng Q, Chiaki Y, Chiapello M, Choi IR, Ciuffo M, Clegg JCS, Crozier I, Dal Bó E, de la Torre JC, de Lamballerie X, de Swart RL, Debat H, Dheilly NM, Di Cicco E, Di Paola N, Di Serio F, Dietzgen RG, Digiaro M, Dolnik O, Drebot MA, Drexler JF, Dundon WG, Duprex WP, Dürrwald R, Dye JM, Easton AJ, Ebihara H, Elbeaino T, Ergünay K, Ferguson HW, Fooks AR, Forgia M, Formenty PBH, Fránová J, Freitas-Astúa J, Fu J, Fürl S, Gago-Zachert S, Gao GF, García ML, García-Sastre A, Garrison AR, Gaskin T, Gonzalez JJ, Griffiths A, Goldberg TL, Groschup MH, Günther S, Hall RA, Hammond J, Han T, Hepojoki J, Hewson R, Hong J, Hong N, Hongo S, Horie M, Hu JS, Hu T, Hughes HR, Hüttner F, Hyndman TH, Ilyas M, Jalkanen R, Jiang D, Jonson GB, Junglen S, Kadono F, Kaukinen KH, Kawate M, Klempa B, Klingström J, Kobinger G, Koloniuk I, Kondo H, Koonin EV, Krupovic M, Kubota K, Kurath G, Laenen L, Lambert AJ, Langevin SL, Lee B, Lefkowitz EJ, Leroy EM, Li S, Li L, Li J, Liu H, Lukashevich IS, Maes P, de Souza WM, Marklewitz M, Marshall SH, Marzano SL, Massart S, McCauley JW, Melzer M, Mielke-Ehret N, Miller KM, Ming TJ, Mirazimi A, Mordecai GJ, Mühlbach HP, Mühlberger E, Naidu R, Natsuaki T, Navarro JA, Netesov SV, Neumann G, Nowotny N, Nunes MRT, Olmedo-Velarde A, Palacios G, Pallás V, Pályi B, Papa A, Paraskevopoulou S, Park AC, Parrish CR, Patterson DA, Pauvolid-Corrêa A, Paweska JT, Payne S, Peracchio C, Pérez DR, Postler TS, Qi L, Radoshitzky SR, Resende RO, Reyes CA, Rima BK, Luna GR, Romanowski V, Rota P, Rubbenstroth D, Rubino L, Runstadler JA, Sabanadzovic S, Sall AA, Salvato MS, Sang R, Sasaya T, Schulze AD, Schwemmle M, Shi M, Shí X, Shí Z, Shimomoto Y, Shirako Y, Siddell SG, Simmonds P, Sironi M, Smagghe G, Smither S, Song JW, Spann K, Spengler JR, Stenglein MD, Stone DM, Sugano J, Suttle CA, Tabata A, Takada A, Takeuchi S, Tchouassi DP, Teffer A, Tesh RB, Thornburg NJ, Tomitaka Y, Tomonaga K, Tordo N, Torto B, Towner JS, Tsuda S, Tu C, Turina M, Tzanetakis IE, Uchida J, Usugi T, Vaira AM, Vallino M, van den Hoogen B, Varsani A, Vasilakis N, Verbeek M, von Bargen S, Wada J, Wahl V, Walker PJ, Wang LF, Wang G, Wang Y, Wang Y, Waqas M, Wèi T, Wen S, Whitfield AE, Williams JV, Wolf YI, Wu J, Xu L, Yanagisawa H, Yang C, Yang Z, Zerbini FM, Zhai L, Zhang YZ, Zhang S, Zhang J, Zhang Z, Zhou X. Correction to: 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales. Arch Virol. 2021 Dec; 166(12):3567-3579.View Related Profiles. PMID: 34786611
     
Showing 10 of 110 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 110 publications over 29 distinct years, with a maximum of 12 publications in 2020

YearPublications
19922
19931
19951
19962
19982
19993
20003
20014
20024
20033
20042
20052
20065
20072
20082
20094
20102
20112
20122
20135
20143
20152
20165
20177
20187
20196
202012
20216
20229

Available to Mentor as: (Review Mentor Role Definitions):
  • Advisor
  • Co-Mentor or Peer Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:

72 E. Concord St Instructional (L)
Boston MA 02118
Google Map


Muhlberger's Networks
Click the "See All" links for more information and interactive visualizations
Concepts
_
Media Mentions
_
Co-Authors
_
Similar People
_
Same Department