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Antibiotic Doxycycline May Offer Hope As Parkinson's Treatment

A recent study suggests that doxycycline can be prescribed at lower doses for the treatment of Parkinson's disease.

The research is in Scientific Reports. (full open access)

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Stroke Prevention May Also Reduce Dementia

Ontario's stroke prevention strategy is also reducing incidence of dementia among people 80+.

The research will is in Alzheimer's Disease and Dementia. (full open access)

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3D Model of NFL Player's Brain Reconstructs Moment of Impact

The study, conducted by researchers at Imperial College London, was carried out to understand in more detail the link between traumatic brain injury (TBI) and chronic traumatic encephalopathy (CTE). The latter is a form of dementia and causes a long-term build-up of proteins called tau, associated with the degeneration of brain tissue and declining health.

The research is in Brain. (full open access)

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CRISPR Used to Edit Stem Cells in Fight Against Arthritis

Using new gene-editing technology, researchers have rewired mouse stem cells to fight inflammation caused by arthritis and other chronic conditions. Such stem cells, known as SMART cells (Stem cells Modified for Autonomous Regenerative Therapy), develop into cartilage cells that produce a biologic anti-inflammatory drug that, ideally, will replace arthritic cartilage and simultaneously protect joints and other tissues from damage that occurs with chronic inflammation.

The research is in Stem Cell Reports. (full open access)

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New Analysis of Brain Network Activity Offers Unique Insight into Epileptic Seizures

University of Bonn researchers are exploring 'evolving epileptic brain networks' to gain a better understanding of brain activity in epilepsy patients and the roles played by different regions of the brain.

The research is in Chaos. (full open access)

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Skin Stem Cells Used to Generate New Brain Cells

UCI-led study to advance understanding of the role of microglia in Alzheimer’s disease.

The research is in Neuron. (full open access)

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Low Levels of Memory Protein Linked to Cognitive Decline in Alzheimer's

Working with human brain tissue samples and genetically engineered mice, Johns Hopkins Medicine researchers together with colleagues at the National Institutes of Health, the University of California San Diego Shiley-Marcos Alzheimer's Disease Research Center, Columbia University, and the Institute for Basic Research in Staten Island say that consequences of low levels of the protein NPTX2 in the brains of people with Alzheimer's disease (AD) may change the pattern of neural activity in ways that lead to the learning and memory loss that are hallmarks of the disease.

The research is in eLife. (full open access)

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Discovery Offers New Hope For Spinal Cord Injury Repair

Gladstone scientists are the first to produce a type of stem cell-derived neuron that could potentially help restore movement.

The research is in PNAS. (full access paywall)

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How Walking Benefits the Brain

Researchers show that foot's impact helps control, increase the amount of blood sent to the brain.

The research will be presented at Experimental Biology 2017.

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Medical History Reveals Multiple Sclerosis Begins to Impact Patients Sooner

People with multiple sclerosis can show signs of something wrong five years before the onset of disease, much earlier than previously thought, according to a new analysis of health records from people with the condition.

The research is in Lancet Neurology. (full access paywall)
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