Tuuli Lappalainen

@tuuliel

Group leader at NY Genome Center & Columbia University, studying functional variation in the human genome.

New York City, NY, USA
Menyertai Mei 2012

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  1. Mengetweet Semula
    2 jam lalu

    This is a huge piece of work on pooled screen for 204 human cell lines from 12 cancer types targeting 18,009 genes for cellular fitness genes -> 6,830 gene loss of fitness -> > 500 core fitness genes => 497 priority genes. In short huge dataset

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  2. Mengetweet Semula
    2 jam lalu

    Could gene-centic functional screens be valuable for functional follow up of results, in addition to the numerous variant-centric approaches being employed? Our preprint applying this approach for blood trait GWAS is posted: (1/2)

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  3. Mengetweet Semula
    5 jam lalu

    Data imitates decorations. One view is of James Hotel across Sixth Avenue, the other a screen on fourth floor of

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  4. Mengetweet Semula
    7 jam lalu

    From abstract of new : "We show that trait associated loci cover more than half of the genome, and 90% of those loci are associated with multiple trait domains." Me: 😮😮🤔. Very cool -- check it out here:

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  5. 8 jam lalu

    Exceptions include my department's pre-award team and others who help me to get $$$

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  6. 10 jam lalu

    PSA: Any company/vendor/institute that emails me a holiday greetings will be blocked.

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  7. Mengetweet Semula
    22 jam lalu

    Our new paper: Using Equivalent Class counts directly for testing differential transcript usage. Nice work from

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  8. Mengetweet Semula
    19 Dis

    Our paper on high-resolution mapping of driver nucleotides in transcriptional regulatory elements is out today! This work from the and labs came together at the very end of my Ph.D. (1/5)

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  9. Mengetweet Semula
    19 Dis
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  10. Mengetweet Semula
    19 Dis
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  11. 19 Dis

    Donations by NYers until 12/31 will be matched 6x, so even small $ now for make a big difference! She's endorsed by e.g. and . Special election will be in February. 2/2

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  12. 19 Dis

    I donated to support campaign for NYC Public Advocate - our watchdog against corruption. She's an activist, journalist, a fierce progressive fighter. Don't take my word, watch this: and donate in 1/2

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  13. Mengetweet Semula
    17 Dis

    Inferring Compensatory Evolution of cis- and trans-Regulatory Variation

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  14. Mengetweet Semula
    17 Dis

    A great issue on human evolutionary genetics edited by Brenna Henn () and myself. Great reviews by great people. Thanks to all. Enjoy it. Current Opinion in Genetics & Development | Genetics of Human Origins |

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  15. 18 Dis

    Congratulations ! Based on productivity during only 5 weeks of postdoc work here, I expect to celebrate more achievements in not too distant future!

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  16. Mengetweet Semula
    16 Dis

    WRITING A PAPER IN WORD: FONT TIPS Contrary to widely held belief (among LaTeX fands), it is easy to write a nice-looking paper in Word. You just have to do three things: (1) use styles; (2) avoid hideous fonts; (3) unleash the fonts’ potential. 2\

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  17. Mengetweet Semula
    18 Dis

    New from the lab. We identified trans- in stimulated /macrophages including risk allele in CLU and MS4A loci influencing distal expression of type 1 , complement and myeloid genes.

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  18. Mengetweet Semula
    18 Dis

    Super excited about our work! A new set test method for association testing using summary statistics.

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  19. 17 Dis

    Looking for advice: our project looks at phenomena across diverse GWAS traits and environmental factors. Is it OK to just apply access to all the data (looks like a lot of clicking though) since we don't know which fields we'll need - or do I need to be more specific?

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  20. Mengetweet Semula
    17 Dis

    Where to go for rare disease diagnoses after exome sequencing fails? Excellent review of the options by and :

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