Frederick Ruberg | Profiles RNS

Frederick L. Ruberg, MD

Associate Professor

Boston University Chobanian & Avedisian School of Medicine

Dept of Medicine

Cardiovascular Medicine

MD, University of Pennsylvania School of Medicine

Pronouns: he/him/his

Websites

	Boston Medical Center Provider Profile
	Boston University School of Medicine Profile

ORCID : 0000-0002-6424-4413

Dr. Ruberg's clinical and research expertise is in the field of cardiac imaging including echocardiography and cardiovascular magnetic resonance imaging (CMR). Dr. Ruberg applies imaging in research designed to facilitate improved diagnosis and management of the infiltrative cardiomyopathy cardiac amyloidosis.

Diversity, Equity, Inclusion and Accessibility

I am deeply committed to developing an equitable and supportive clinical and research environment at BU/BMC. Through my nearly 2 decades of experience and leadership at BU/BMC, I have been focused on increasing representation of women and under-represented minority groups in medicine (URiM) in the clinical workforce while working to ensure that such populations are appropriately represented in research programs. Under my leadership as Program Director of the clinical fellowship training program and now Associate Chief of Cardiovascular Medicine, the cardiovascular medicine fellowship has achieved an approximate 50% women trainee census, and presently exceeds national census means for trainees who identify as URiM in cardiovascular medicine. I also serve as the Section lead of the BUMG campus-wide Commitment to Operationalize Racial Equity (CORE) program (to define and meet racial equity goals) and served as a member of the Department of Medicine Faculty Development and Diversity Committee before transitioning to my current position on the BUMG Women’s Leadership Advisory Council. My current clinical research team reflects this commitment, composed nearly entirely of women and/or URiM trainees. My primary research focus, hereditary transthyretin cardiac amyloidosis (ATTR), is a heart disease that disproportionately affects patients identifying as Black. I have served as PI on two awards from NIH that specifically focus on ATTR cardiac amyloidosis (most notably the ongoing Screening for Cardiac Amyloidosis with Nuclear Imaging in Minority Populations, or SCAN-MP study). Finally, since 2016, I have also meaningfully contributed to development of a diverse scientific workforce at BU by facilitating the careers of early investigators through my role as Director of Pilot Grant Award Program at the BU Clinical and Translational Science Institute.

Associate Professor
Boston University Chobanian & Avedisian School of Medicine
Radiology

Member
Boston University
Whitaker Cardiovascular Institute

Member
Boston University
Amyloidosis Center

Program Director
Boston University Chobanian & Avedisian School of Medicine
Clinical and Translational Science Institute
Pilot Translational & Clinical Studies Program

Molecular Imaging of Primary Amyloid Cardiomyopathy
04/01/2017 - 03/31/2020 (Subcontract PI)
The Brigham and Women's Hospital, Inc. NIH NHLBI
5R01HL130563-04

Gadolinium-Free Myocardial Scar and Fibrosis Imaging with Ca
07/01/2020 - 06/30/2024 (PI)
Beth Israel Deaconess Medical Center National Heart, Lung

Scan-MP (Screening fro cardiac amyloidosis with nuclear imag
05/01/2019 - 02/29/2024 (PI)
The Trustees of Colombia University in the City of New York dba Colombia University National Heart, Lung

Screening for ATTR Amyloidosis among patients undergoing lumbar spinal stenosis decompression…
02/11/2020 - 02/11/2023 (PI)
Akcea Therapeutics, Inc

2020 RD L – Cardiac Amyloidosis Fellowship U.S
10/26/2020 - 10/25/2022 (PI)
Pfizer, Inc

2021 Transthyretin Cardiac Amyloidosis Fellowship
10/14/2021 - 10/13/2022 (PI)
Pfizer, Inc

Alnylam - MGH study agreement (2019A017487)
09/01/2020 - 08/31/2022 (PI)
Massachusetts General Hospital Alnylam Pharmaceutic

SCAN-MP Supplement SCREENING FOR CARDIAC AMYLOIDOSIS WITH NUCLEAR IMAGING IN MINORITY POPULATIONS (SCAN-MP) STUDY
09/01/2020 - 08/31/2022 (PI)
Trustees of Columbia University National Heart, Lung

Longitudinal strain in ATTR cardiac amyloidosis
09/25/2017 - 09/25/2021 (PI)
Eidos Therapeutics

Cardiac Amyloidosis Fellowship
01/01/2019 - 07/01/2021 (PI)
Pfizer, Inc

2019 US ASPIRE for TTR Amyloidosis
09/23/2019 - 06/03/2021 (PI)
Tufts Medical Center Pfizer, Inc

Showing 10 of 17 results. Show All Results

Title

Yr	Title	Project-Sub Proj	Pubs
2022	SCAN-MP (Screening for Cardiac Amyloidosiswith Nuclear imaging in Minority Populations)	5R01HL139671-04
2021	SCAN-MP (Screening for Cardiac Amyloidosiswith Nuclear imaging in Minority Populations)	5R01HL139671-03	5
2020	SCAN-MP (Screening for Cardiac Amyloidosis with Nuclear imaging in Minority Populations) COVID-19 Suppplement	3R01HL139671-02S1	5
2020	SCAN-MP (Screening for Cardiac Amyloidosiswith Nuclear imaging in Minority Populations)	5R01HL139671-02	5
2019	SCAN-MP (Screening for Cardiac Amyloidosiswith Nuclear imaging in Minority Populations)	1R01HL139671-01A1	5
2016	Serum biomarker identification of cardiac amyloidosis in elderly African Americans.	5R21AG050206-02	9
2015	Serum biomarker identification of cardiac amyloidosis in elderly African Americans.	1R21AG050206-01	9

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Rowin EJ, Ruberg FL, Das G, Higgins D, Lipe WC, Bokhari N, Dehn M, Maron BJ, Maron MS. Identification of Transthyretin Cardiac Amyloidosis Among Patients Previously Diagnosed With Hypertrophic Cardiomyopathy. Circ Cardiovasc Imaging. 2022 Dec; 15(12):e014938. PMID: 36448453; DOI: 10.1161/CIRCIMAGING.122.014938;

Cuddy SA, Datar Y, Ovsak G, Saith S, Murphy SP, Bay CP, Haddad M, Lilleness B, Muralidhar V, Pipilas A, Vuong J, Guardino E, Maurer MS, Ruberg FL, Falk RH, Dorbala S. Optimal Echocardiographic Parameters to Improve the Diagnostic Yield of Tc-99m-Bone Avid Tracer Cardiac Scintigraphy for Transthyretin Cardiac Amyloidosis. Circ Cardiovasc Imaging. 2022 Nov; 15(11):e014645. PMID: 36378779; PMCID: PMC9667717; DOI: 10.1161/CIRCIMAGING.122.014645;

Minnema MC, Dispenzieri A, Merlini G, Comenzo RL, Kastritis E, Wechalekar AD, Grogan M, Witteles R, Ruberg FL, Maurer MS, Tran N, Qin X, Vasey SY, Weiss BM, Vermeulen J, Jaccard A. Outcomes by Cardiac Stage in Patients With Newly Diagnosed AL Amyloidosis: Phase 3 ANDROMEDA Trial. JACC CardioOncol. 2022 Nov; 4(4):474-487. PMID: 36444227; PMCID: PMC9700253; DOI: 10.1016/j.jaccao.2022.08.011;

Alreshq R, Cozzolino M, Lilleness B, Pipilas A, Mendelson L, Joshi T, Muralidhar V, Guardino E, Berk JL, Siddiqi OK, Gopal DM, Sanchorawala V, Ruberg FL. Light Chain Testing Abnormalities Among Patients With Transthyretin Amyloid Cardiomyopathy Referred for Technetium-99m Pyrophosphate Imaging. Am J Cardiol. 2022 Oct 15; 181:105-112. PMID: 36028388; PMCID: PMC9675982; DOI: 10.1016/j.amjcard.2022.06.064;

Tahir UA, Katz DH, Avila-Pachecho J, Bick AG, Pampana A, Robbins JM, Yu Z, Chen ZZ, Benson MD, Cruz DE, Ngo D, Deng S, Shi X, Zheng S, Eisman AS, Farrell L, Hall ME, Correa A, Tracy RP, Durda P, Taylor KD, Liu Y, Johnson WC, Guo X, Yao J, Chen YI, Manichaikul AW, Ruberg FL, Blaner WS, Jain D, Bouchard C, Sarzynski MA, Rich SS, Rotter JI, Wang TJ, Wilson JG, Clish CB, Natarajan P, Gerszten RE. Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals. Nat Commun. 2022 08 22; 13(1):4923. PMID: 35995766; PMCID: PMC9395431; DOI: 10.1038/s41467-022-32275-3;

Schwartz B, Schou M, Ruberg FL, Rucker D, Choi J, Siddiqi O, Monahan K, Køber L, Gislason G, Torp-Pedersen C, Andersson C. Cardiovascular Morbidity in Monoclonal Gammopathy of Undetermined Significance: A Danish Nationwide Study. JACC CardioOncol. 2022 Sep; 4(3):313-322. PMID: 36213365; PMCID: PMC9537076; DOI: 10.1016/j.jaccao.2022.05.009;

Gustine JN, Staron A, Szalat RE, Mendelson LM, Joshi T, Ruberg FL, Siddiqi O, Gopal DM, Edwards CV, Havasi A, Kaku M, Lau KHV, Berk JL, Sloan JM, Sanchorawala V. Predictors of hematologic response and survival with stem cell transplantation in AL amyloidosis: A 25-year longitudinal study. Am J Hematol. 2022 Sep; 97(9):1189-1199.View Related Profiles.

Staron, Andrew
Edwards, Camille
Gopal, Deepa
Ruberg, Frederick
Sloan, J.
Berk, John
Lau, K.H. Vincent
Mendelson, Lisa
Kaku, Michelle
Siddiqi, Omar
Szalat, Raphael
Joshi, Tracy
Sanchorawala, Vaishali

PMID: 35731907

Poterucha TJ, Kurian D, Raiszadeh F, Teruya S, Elias P, Kogan R, Chiuzan C, Einstein AJ, Ruberg FL, Maurer MS. Relation of Body Mass Index to Transthyretin Cardiac Amyloidosis Particularly in Black and Hispanic Patients (from the SCAN-MP Study). Am J Cardiol. 2022 Aug 15; 177:116-120. PMID: 35705430

Siddiqi OK, Mints YY, Berk JL, Connors L, Doros G, Gopal DM, Kataria S, Lohrmann G, Pipilas AR, Ruberg FL. Diflunisal treatment is associated with improved survival for patients with early stage wild-type transthyretin (ATTR) amyloid cardiomyopathy: the Boston University Amyloidosis Center experience. Amyloid. 2022 Jun; 29(2):71-78.View Related Profiles.

Gopal, Deepa
Ruberg, Frederick
Doros, Gheorghe
Berk, John
Connors, Lawreen
Siddiqi, Omar

PMID: 35083944; PMCID: PMC9258521; DOI: 10.1080/13506129.2021.2000388;

Oster ME, Shay DK, Su JR, Gee J, Creech CB, Broder KR, Edwards K, Soslow JH, Dendy JM, Schlaudecker E, Lang SM, Barnett ED, Ruberg FL, Smith MJ, Campbell MJ, Lopes RD, Sperling LS, Baumblatt JA, Thompson DL, Marquez PL, Strid P, Woo J, Pugsley R, Reagan-Steiner S, DeStefano F, Shimabukuro TT. Myocarditis Cases Reported After mRNA-Based COVID-19 Vaccination in the US From December 2020 to August 2021. JAMA. 2022 01 25; 327(4):331-340.View Related Profiles.

Barnett, Elizabeth
Ruberg, Frederick

PMID: 35076665; PMCID: PMC8790664; DOI: 10.1001/jama.2021.24110;

Showing 10 of 109 results. Show More

Cuddy SAM, Jerosch-Herold M, Falk RH, Kijewski MF, Singh V, Ruberg FL, Sanchorawala V, Landau H, Maurer MS, Yee AJ, Bianchi G, Di Carli MF, Liao R, Kwong RY, Dorbala S. Myocardial Composition in Light-Chain Cardiac Amyloidosis More Than 1 Year After Successful Therapy. JACC Cardiovasc Imaging. 2022 Apr; 15(4):594-603.View Related Profiles.

Ruberg, Frederick
Sanchorawala, Vaishali

PMID: 34922860; PMCID: PMC8995332; DOI: 10.1016/j.jcmg.2021.09.032;

Ruberg FL. Phenotype Mapping in Cardiac Amyloidosis. J Am Coll Cardiol. 2021 11 30; 78(22):2193-2195. PMID: 34823662

Alreshq R, Tugal D, Siddiqi O, Ruberg F. Conduction abnormalities and role of cardiac pacing in cardiac amyloidosis: A systematic review. Pacing Clin Electrophysiol. 2021 Dec; 44(12):2092-2099.View Related Profiles.

Tugal, Derin
Ruberg, Frederick
Siddiqi, Omar

PMID: 34632598

Maurer MS, Ruberg FL. Cardiac Scintigraphy and Screening for Transthyretin Cardiac Amyloidosis: Caveat Emptor. Circulation. 2021 09 28; 144(13):1005-1007. PMID: 34570590; PMCID: PMC8483571; DOI: 10.1161/CIRCULATIONAHA.121.055517;

Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI Expert Consensus Recommendations for Multimodality Imaging in Cardiac Amyloidosis: Part 2 of 2-Diagnostic Criteria and Appropriate Utilization. Circ Cardiovasc Imaging. 2021 07; 14(7):e000030. PMID: 34196222

Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI Expert Consensus Recommendations for Multimodality Imaging in Cardiac Amyloidosis: Part 1 of 2-Evidence Base and Standardized Methods of Imaging. Circ Cardiovasc Imaging. 2021 07; 14(7):e000029. PMID: 34196223

Patel RK, Fontana M, Ruberg FL. Cardiac Amyloidosis: Multimodal Imaging of Disease Activity and Response to Treatment. Circ Cardiovasc Imaging. 2021 06; 14(6):e009025. PMID: 34129344; PMCID: PMC8210461; DOI: 10.1161/CIRCIMAGING.121.009025;

Poterucha TJ, Elias P, Ruberg FL, DeLuca A, Kinkhabwala M, Johnson LL, Griffin JM, Pandey S, Einstein AJ, Maurer MS. False Positive 99mTc-Pyrophosphate Scanning Leading to Inappropriate Tafamidis Prescriptions. JACC Cardiovasc Imaging. 2021 10; 14(10):2042-2044.View Related Profiles.

Ruberg, Frederick
Pandey, Shivda

PMID: 34023264

Brannagan TH, Auer-Grumbach M, Berk JL, Briani C, Bril V, Coelho T, Damy T, Dispenzieri A, Drachman BM, Fine N, Gaggin HK, Gertz M, Gillmore JD, Gonzalez E, Hanna M, Hurwitz DR, Khella SL, Maurer MS, Nativi-Nicolau J, Olugemo K, Quintana LF, Rosen AM, Schmidt HH, Shehata J, Waddington-Cruz M, Whelan C, Ruberg FL. ATTR amyloidosis during the COVID-19 pandemic: insights from a global medical roundtable. Orphanet J Rare Dis. 2021 05 06; 16(1):204.View Related Profiles.

Ruberg, Frederick
Berk, John

PMID: 33957949; PMCID: PMC8100737; DOI: 10.1186/s13023-021-01834-0;

Alreshq R, Ruberg FL. Clinical approach to genetic testing in amyloid cardiomyopathy: from mechanism to effective therapies. Curr Opin Cardiol. 2021 05 01; 36(3):309-317. PMID: 33605615; PMCID: PMC8221237; DOI: 10.1097/HCO.0000000000000841;

Lohrmann G, Patel MA, Brauneis D, Sanchorawala V, Sarosiek S, Vellanki N, Siddiqi OK, Ruberg FL, Gopal DM. Left Atrial Mechanics Associates With Paroxysmal Atrial Fibrillation in Light-Chain Amyloidosis Following Stem Cell Transplantation. JACC CardioOncol. 2020 Dec; 2(5):721-731.View Related Profiles.

Gopal, Deepa
Ruberg, Frederick
Siddiqi, Omar
Sarosiek, Shayna
Sanchorawala, Vaishali

PMID: 33511355; PMCID: PMC7839967; DOI: 10.1016/j.jaccao.2020.10.010;

Ruberg FL, Siddiqi OK. In Search of the Holy Grail: Evidence of Amyloid Fibril Regression in ATTR Cardiac Amyloidosis. JACC Cardiovasc Imaging. 2021 01; 14(1):200-202.View Related Profiles.

Ruberg, Frederick
Siddiqi, Omar

PMID: 33129738; PMCID: PMC8543316; DOI: 10.1016/j.jcmg.2020.08.021;

Poterucha TJ, Elias P, Ruberg FL, DeLuca A, Kinkhabwala M, Johnson LL, Maurer MS, Einstein AJ. The importance of SPECT cardiac reconstruction for accurate 99mTc-pyrophosphate interpretation in TTR amyloidosis. J Nucl Cardiol. 2022 Jun; 29(3):1478-1480. PMID: 33118142; DOI: 10.1007/s12350-020-02409-5;

Gertz M, Adams D, Ando Y, Beirão JM, Bokhari S, Coelho T, Comenzo RL, Damy T, Dorbala S, Drachman BM, Fontana M, Gillmore JD, Grogan M, Hawkins PN, Lousada I, Kristen AV, Ruberg FL, Suhr OB, Maurer MS, Nativi-Nicolau J, Quarta CC, Rapezzi C, Witteles R, Merlini G. Avoiding misdiagnosis: expert consensus recommendations for the suspicion and diagnosis of transthyretin amyloidosis for the general practitioner. BMC Fam Pract. 2020 09 23; 21(1):198. PMID: 32967612; PMCID: PMC7513485; DOI: 10.1186/s12875-020-01252-4;

Hanna M, Ruberg FL, Maurer MS, Dispenzieri A, Dorbala S, Falk RH, Hoffman J, Jaber W, Soman P, Witteles RM, Grogan M. Cardiac Scintigraphy With Technetium-99m-Labeled Bone-Seeking Tracers for Suspected Amyloidosis: JACC Review Topic of the Week. J Am Coll Cardiol. 2020 06 09; 75(22):2851-2862. PMID: 32498813; DOI: 10.1016/j.jacc.2020.04.022;

Kittleson MM, Maurer MS, Ambardekar AV, Bullock-Palmer RP, Chang PP, Eisen HJ, Nair AP, Nativi-Nicolau J, Ruberg FL. Cardiac Amyloidosis: Evolving Diagnosis and Management: A Scientific Statement From the American Heart Association. Circulation. 2020 07 07; 142(1):e7-e22. PMID: 32476490; DOI: 10.1161/CIR.0000000000000792;

Cuddy SAM, Bravo PE, Falk RH, El-Sady S, Kijewski MF, Park MA, Ruberg FL, Sanchorawala V, Landau H, Yee AJ, Bianchi G, Di Carli MF, Cheng SC, Jerosch-Herold M, Kwong RY, Liao R, Dorbala S. Improved Quantification of Cardiac Amyloid Burden in Systemic Light Chain Amyloidosis: Redefining Early Disease? JACC Cardiovasc Imaging. 2020 06; 13(6):1325-1336.View Related Profiles.

Ruberg, Frederick
Sanchorawala, Vaishali

PMID: 32417333; PMCID: PMC8218539; DOI: 10.1016/j.jcmg.2020.02.025;

Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI expert consensus recommendations for multimodality imaging in cardiac amyloidosis: Part 2 of 2-Diagnostic criteria and appropriate utilization. J Nucl Cardiol. 2020 04; 27(2):659-673. PMID: 31468377

Ruberg FL, Siddiqi OK. Hepatocyte Growth Factor and Cardiac Amyloidosis. JACC CardioOncol. 2020 Mar; 2(1):67-69.View Related Profiles.

Ruberg, Frederick
Siddiqi, Omar

PMID: 32647833; PMCID: PMC7347296; DOI: 10.1016/j.jaccao.2020.02.004;

Khor YM, Cuddy S, Harms HJ, Kijewski MF, Park MA, Robertson M, Hyun H, Di Carli MF, Bianchi G, Landau H, Yee A, Sanchorawala V, Ruberg FL, Liao R, Berk J, Falk RH, Dorbala S. Quantitative [18F]florbetapir PET/CT may identify lung involvement in patients with systemic AL amyloidosis. Eur J Nucl Med Mol Imaging. 2020 07; 47(8):1998-2009.View Related Profiles.

Ruberg, Frederick
Berk, John
Sanchorawala, Vaishali

PMID: 31807884; PMCID: PMC8202062; DOI: 10.1007/s00259-019-04627-7;

Lohrmann G, Pipilas A, Mussinelli R, Gopal DM, Berk JL, Connors LH, Vellanki N, Hellawell J, Siddiqi OK, Fox J, Maurer MS, Ruberg FL. Stabilization of Cardiac Function With Diflunisal in Transthyretin (ATTR) Cardiac Amyloidosis. J Card Fail. 2020 Sep; 26(9):753-759.View Related Profiles.

Pipilas, Alexandra
Gopal, Deepa
Ruberg, Frederick
Berk, John
Connors, Lawreen
Siddiqi, Omar

PMID: 31805416; PMCID: PMC7758872; DOI: 10.1016/j.cardfail.2019.11.024;

Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI expert consensus recommendations for multimodality imaging in cardiac amyloidosis: Part 1 of 2-evidence base and standardized methods of imaging. J Nucl Cardiol. 2019 12; 26(6):2065-2123. PMID: 31468376

Gopal DM, Ruberg FL, Siddiqi OK. Impact of Genetic Testing in Transthyretin (ATTR) Cardiac Amyloidosis. Curr Heart Fail Rep. 2019 10; 16(5):180-188.View Related Profiles.

Gopal, Deepa
Ruberg, Frederick
Siddiqi, Omar

PMID: 31520266

Lilleness B, Doros G, Ruberg FL, Sanchorawala V. Establishment of brain natriuretic peptide - based criteria for evaluating cardiac response to treatment in light chain (AL) amyloidosis. Br J Haematol. 2020 02; 188(3):424-427.View Related Profiles.

Ruberg, Frederick
Doros, Gheorghe
Sanchorawala, Vaishali

PMID: 31515797

Maurer MS, Bokhari S, Damy T, Dorbala S, Drachman BM, Fontana M, Grogan M, Kristen AV, Lousada I, Nativi-Nicolau J, Cristina Quarta C, Rapezzi C, Ruberg FL, Witteles R, Merlini G. Expert Consensus Recommendations for the Suspicion and Diagnosis of Transthyretin Cardiac Amyloidosis. Circ Heart Fail. 2019 09; 12(9):e006075. PMID: 31480867; PMCID: PMC6736650; DOI: 10.1161/CIRCHEARTFAILURE.119.006075;

Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI Expert Consensus Recommendations for Multimodality Imaging in Cardiac Amyloidosis: Part 1 of 2-Evidence Base and Standardized Methods of Imaging. J Card Fail. 2019 Nov; 25(11):e1-e39. PMID: 31473268; DOI: 10.1016/j.cardfail.2019.08.001;

Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI Expert Consensus Recommendations for Multimodality Imaging in Cardiac Amyloidosis: Part 2 of 2-Diagnostic Criteria and Appropriate Utilization. J Card Fail. 2019 Nov; 25(11):854-865. PMID: 31473267; DOI: 10.1016/j.cardfail.2019.08.002;

Staron A, Connors LH, Ruberg FL, Mendelson LM, Sanchorawala V. A new era of amyloidosis: the trends at a major US referral centre. Amyloid. 2019 Dec; 26(4):192-196.View Related Profiles.

Staron, Andrew
Ruberg, Frederick
Connors, Lawreen
Mendelson, Lisa
Sanchorawala, Vaishali

PMID: 31306033

Ruberg FL, Grogan M, Hanna M, Kelly JW, Maurer MS. Transthyretin Amyloid Cardiomyopathy: JACC State-of-the-Art Review. J Am Coll Cardiol. 2019 06 11; 73(22):2872-2891. PMID: 31171094; PMCID: PMC6724183; DOI: 10.1016/j.jacc.2019.04.003;

Ehman EC, El-Sady MS, Kijewski MF, Khor YM, Jacob S, Ruberg FL, Sanchorawala V, Landau H, Yee AJ, Bianchi G, Di Carli MF, Falk RH, Hyun H, Dorbala S. Early Detection of Multiorgan Light-Chain Amyloidosis by Whole-Body 18F-Florbetapir PET/CT. J Nucl Med. 2019 09; 60(9):1234-1239.View Related Profiles.

Ruberg, Frederick
Sanchorawala, Vaishali

PMID: 30954943; PMCID: PMC6735282; DOI: 10.2967/jnumed.118.221770;

Maurer MS, Ruberg FL. Early Diagnosis of Cardiac Amyloidosis by Carpal Tunnel Surgery: Is it All in the Wrist? J Am Coll Cardiol. 2018 10 23; 72(17):2051-2053. PMID: 30336829

Lilleness B, Ruberg FL, Mussinelli R, Doros G, Sanchorawala V. Development and validation of a survival staging system incorporating BNP in patients with light chain amyloidosis. Blood. 2019 01 17; 133(3):215-223.View Related Profiles.

Lilleness, Brian
Ruberg, Frederick
Doros, Gheorghe
Sanchorawala, Vaishali

PMID: 30333122

Mints YY, Doros G, Berk JL, Connors LH, Ruberg FL. Features of atrial fibrillation in wild-type transthyretin cardiac amyloidosis: a systematic review and clinical experience. ESC Heart Fail. 2018 10; 5(5):772-779.View Related Profiles.

Ruberg, Frederick
Doros, Gheorghe
Berk, John
Connors, Lawreen
Mints, Yuliya

PMID: 29916559; PMCID: PMC6165925; DOI: 10.1002/ehf2.12308;

Siddiqi OK, Sanchorawala V, Ruberg FL. Echocardiography and Survival in Light Chain Cardiac Amyloidosis: Back to Basics. Circ Cardiovasc Imaging. 2018 05; 11(5):e007826.View Related Profiles.

Ruberg, Frederick
Siddiqi, Omar
Sanchorawala, Vaishali

PMID: 29752394

Martinez-Naharro A, Kotecha T, Norrington K, Boldrini M, Rezk T, Quarta C, Treibel TA, Whelan CJ, Knight DS, Kellman P, Ruberg FL, Gillmore JD, Moon JC, Hawkins PN, Fontana M. Native T1 and Extracellular Volume in Transthyretin Amyloidosis. JACC Cardiovasc Imaging. 2019 05; 12(5):810-819. PMID: 29550324

Jhaveri T, Sarosiek S, Ruberg FL, Siddiqi O, Berk JL, Sanchorawala V. Once AL amyloidosis: not always AL amyloidosis. Amyloid. 2018 Jun; 25(2):139-140.View Related Profiles.

Ruberg, Frederick
Berk, John
Siddiqi, Omar
Sarosiek, Shayna
Sanchorawala, Vaishali

PMID: 29516761

Phull P, Sanchorawala V, Connors LH, Doros G, Ruberg FL, Berk JL, Sarosiek S. Monoclonal gammopathy of undetermined significance in systemic transthyretin amyloidosis (ATTR). Amyloid. 2018 Mar; 25(1):62-67.View Related Profiles.

Ruberg, Frederick
Doros, Gheorghe
Berk, John
Connors, Lawreen
Phull, Pooja
Sarosiek, Shayna
Sanchorawala, Vaishali

PMID: 29424556; PMCID: PMC6157907; DOI: 10.1080/13506129.2018.1436048;

Hanson JLS, Arvanitis M, Koch CM, Berk JL, Ruberg FL, Prokaeva T, Connors LH. Use of Serum Transthyretin as a Prognostic Indicator and Predictor of Outcome in Cardiac Amyloid Disease Associated With Wild-Type Transthyretin. Circ Heart Fail. 2018 02; 11(2):e004000.View Related Profiles.

Koch, Clarissa
Ruberg, Frederick
Berk, John
Connors, Lawreen
Prokaeva, Tatiana

PMID: 29449366; PMCID: PMC5819619; DOI: 10.1161/CIRCHEARTFAILURE.117.004000;

Maurer MS, Ruberg FL, Weinsaft JW. More Than Meets the Eye: Time for a New Imaging Paradigm to Test for Cardiac Amyloidosis. J Card Fail. 2018 02; 24(2):87-89. PMID: 29305971

Arvanitis M, Chan GG, Jacobson DR, Berk JL, Connors LH, Ruberg FL. Prevalence of mutant ATTR cardiac amyloidosis in elderly African Americans with heart failure. Amyloid. 2017 12; 24(4):253-255.View Related Profiles.

Jacobson, Daniel
Ruberg, Frederick
Berk, John
Connors, Lawreen

PMID: 29052438; PMCID: PMC5894279; DOI: 10.1080/13506129.2017.1391086;

Salinaro F, Meier-Ewert HK, Miller EJ, Pandey S, Sanchorawala V, Berk JL, Seldin DC, Ruberg FL. Longitudinal systolic strain, cardiac function improvement, and survival following treatment of light-chain (AL) cardiac amyloidosis. Eur Heart J Cardiovasc Imaging. 2017 Sep 01; 18(9):1057-1064.View Related Profiles.

Ruberg, Frederick
Meier-Ewert, Hans Kilian
Berk, John
Pandey, Shivda
Sanchorawala, Vaishali

PMID: 27965280; DOI: 10.1093/ehjci/jew298;

Arun M, Brauneis D, Doros G, Shelton AC, Sloan JM, Quillen K, Ruberg FL, Sanchorawala V, Varga C. The incidence of atrial fibrillation among patients with AL amyloidosis undergoing high-dose melphalan and stem cell transplantation: experience at a single institution. Bone Marrow Transplant. 2017 09; 52(9):1349-1351.View Related Profiles.

Ruberg, Frederick
Doros, Gheorghe
Sloan, J.
Quillen, Karen
Sanchorawala, Vaishali

PMID: 28737773

Siddiqi OK, Ruberg FL. Cardiac amyloidosis: An update on pathophysiology, diagnosis, and treatment. Trends Cardiovasc Med. 2018 01; 28(1):10-21.View Related Profiles.

Ruberg, Frederick
Siddiqi, Omar

PMID: 28739313; PMCID: PMC5741539; DOI: 10.1016/j.tcm.2017.07.004;

Siddiqi OK, Ruberg FL. Challenging the myths of cardiac amyloidosis. Eur Heart J. 2017 06 21; 38(24):1909-1912.View Related Profiles.

Ruberg, Frederick
Siddiqi, Omar

PMID: 28444296; DOI: 10.1093/eurheartj/ehx210;

Ruberg FL. Cardiac Amyloidosis: A Zebra Hiding in Plain Sight? Circ Cardiovasc Imaging. 2017 03; 10(3):e006186. PMID: 28298289; DOI: 10.1161/CIRCIMAGING.117.006186;

Arvanitis M, Simon S, Chan G, Fine D, Beardsley P, LaValley M, Jacobson D, Koch C, Berk JL, Connors LH, Ruberg FL. Retinol binding protein 4 (RBP4) concentration identifies V122I transthyretin cardiac amyloidosis. Amyloid. 2017 Mar; 24(sup1):120-121.View Related Profiles.

Koch, Clarissa
Jacobson, Daniel
Ruberg, Frederick
Berk, John
Connors, Lawreen
LaValley, Michael

PMID: 28434357; PMCID: PMC5497748; DOI: 10.1080/13506129.2017.1295371;

Di Carli MF, Davidoff R, Beerbaum P, Dorbala S, Gillam LD, Hoffmann U, Raman SV, Ruberg FL. Editor's Note. Circ Cardiovasc Imaging. 2017 03; 10(3).View Related Profiles.

Ruberg, Frederick
Davidoff, Ravin

PMID: 28289023; DOI: 10.1161/CIRCIMAGING.117.006334;

Arvanitis M, Koch CM, Chan GG, Torres-Arancivia C, LaValley MP, Jacobson DR, Berk JL, Connors LH, Ruberg FL. Identification of Transthyretin Cardiac Amyloidosis Using Serum Retinol-Binding Protein 4 and a Clinical Prediction Model. JAMA Cardiol. 2017 03 01; 2(3):305-313.View Related Profiles.

Koch, Clarissa
Jacobson, Daniel
Ruberg, Frederick
Berk, John
Connors, Lawreen
LaValley, Michael

PMID: 28196196; PMCID: PMC5497744; DOI: 10.1001/jamacardio.2016.5864;

Maurer M, Lousada I, Hanna M, Ruberg F, Mohty D, Dispenzieri A, Liedtke M, Paulson I, Vest J, Grogan M. Recommendations from the Amyloidosis Research Consortium Educational Roundtable at the American College of Cardiology Annual Meeting, 1 April 2016. Amyloid. 2017 Mar; 24(sup1):165-166. PMID: 28434366; DOI: 10.1080/13506129.2017.1286582;

Buxbaum JN, Ruberg FL. Transthyretin V122I (pV142I)* cardiac amyloidosis: an age-dependent autosomal dominant cardiomyopathy too common to be overlooked as a cause of significant heart disease in elderly African Americans. Genet Med. 2017 Jul; 19(7):733-742. PMID: 28102864; PMCID: PMC5509498; DOI: 10.1038/gim.2016.200;

Ruberg FL, Fontana M, Gillmore JD. Should Histologic Determination of Amyloid Load Determine Management Decisions in Light-Chain Amyloidosis? J Am Coll Cardiol. 2016 12 06; 68(22):2493-2494. PMID: 27908360; DOI: 10.1016/j.jacc.2016.07.786;

Castano A, Haq M, Narotsky DL, Goldsmith J, Weinberg RL, Morgenstern R, Pozniakoff T, Ruberg FL, Miller EJ, Berk JL, Dispenzieri A, Grogan M, Johnson G, Bokhari S, Maurer MS. Multicenter Study of Planar Technetium 99m Pyrophosphate Cardiac Imaging: Predicting Survival for Patients With ATTR Cardiac Amyloidosis. JAMA Cardiol. 2016 11 01; 1(8):880-889.View Related Profiles.

Ruberg, Frederick
Berk, John

PMID: 27557400; DOI: 10.1001/jamacardio.2016.2839;

Haq M, Pawar S, Berk JL, Miller EJ, Ruberg FL. Can 99mTc-Pyrophosphate Aid in Early Detection of Cardiac Involvement in Asymptomatic Variant TTR Amyloidosis? JACC Cardiovasc Imaging. 2017 06; 10(6):713-714.View Related Profiles.

Ruberg, Frederick
Berk, John

PMID: 27568122; PMCID: PMC5318295; DOI: 10.1016/j.jcmg.2016.06.003;

Ahmadian A, Pawar S, Govender P, Berman J, Ruberg FL, Miller EJ. The response of FDG uptake to immunosuppressive treatment on FDG PET/CT imaging for cardiac sarcoidosis. J Nucl Cardiol. 2017 Apr; 24(2):413-424.View Related Profiles.

Ruberg, Frederick
Berman, Jeffrey
Govender, Praveen

PMID: 27457527; DOI: 10.1007/s12350-016-0490-7;

Gillmore JD, Maurer MS, Falk RH, Merlini G, Damy T, Dispenzieri A, Wechalekar AD, Berk JL, Quarta CC, Grogan M, Lachmann HJ, Bokhari S, Castano A, Dorbala S, Johnson GB, Glaudemans AW, Rezk T, Fontana M, Palladini G, Milani P, Guidalotti PL, Flatman K, Lane T, Vonberg FW, Whelan CJ, Moon JC, Ruberg FL, Miller EJ, Hutt DF, Hazenberg BP, Rapezzi C, Hawkins PN. Nonbiopsy Diagnosis of Cardiac Transthyretin Amyloidosis. Circulation. 2016 Jun 14; 133(24):2404-12.View Related Profiles.

Ruberg, Frederick
Berk, John

PMID: 27143678; DOI: 10.1161/CIRCULATIONAHA.116.021612;

Jefferson AL, Gifford KA, Acosta LM, Bell SP, Donahue MJ, Davis LT, Gottlieb J, Gupta DK, Hohman TJ, Lane EM, Libon DJ, Mendes LA, Niswender K, Pechman KR, Rane S, Ruberg FL, Su YR, Zetterberg H, Liu D. The Vanderbilt Memory & Aging Project: Study Design and Baseline Cohort Overview. J Alzheimers Dis. 2016 03 08; 52(2):539-59.View Related Profiles.

Ruberg, Frederick
Gifford, Katherine

PMID: 26967211; PMCID: PMC4866875; DOI: 10.3233/JAD-150914;

Connors LH, Sam F, Skinner M, Salinaro F, Sun F, Ruberg FL, Berk JL, Seldin DC. Heart Failure Resulting From Age-Related Cardiac Amyloid Disease Associated With Wild-Type Transthyretin: A Prospective, Observational Cohort Study. Circulation. 2016 Jan 19; 133(3):282-90.View Related Profiles.

Sun, Fangui
Sam, Flora
Ruberg, Frederick
Berk, John
Connors, Lawreen
Skinner, Martha

PMID: 26660282; PMCID: PMC4718760; DOI: 10.1161/CIRCULATIONAHA.115.018852;

Ruberg FL, Nezafat R. Cardiovascular Magnetic Resonance Visualization of Cardiac Amyloid Infiltration: Challenges and Opportunities. Circulation. 2015 Oct 20; 132(16):1525-7. PMID: 26362630; PMCID: PMC4725194; DOI: 10.1161/CIRCULATIONAHA.115.018832;

Hohman TJ, Samuels LR, Liu D, Gifford KA, Mukherjee S, Benson EM, Abel T, Ruberg FL, Jefferson AL. Stroke risk interacts with Alzheimer's disease biomarkers on brain aging outcomes. Neurobiol Aging. 2015 Sep; 36(9):2501-8.View Related Profiles.

Ruberg, Frederick
Gifford, Katherine

PMID: 26119224; PMCID: PMC4523400; DOI: 10.1016/j.neurobiolaging.2015.05.021;

Ruberg FL, Berk JL, Semigan MJ. V122I transthyretin variant in elderly black Americans. N Engl J Med. 2015 Apr 30; 372(18):1768.View Related Profiles.

Ruberg, Frederick
Berk, John

PMID: 25923563; DOI: 10.1056/NEJMc1503222#SA1;

Jefferson AL, Hohman TJ, Liu D, Haj-Hassan S, Gifford KA, Benson EM, Skinner JS, Lu Z, Sparling J, Sumner EC, Bell S, Ruberg FL. Adverse vascular risk is related to cognitive decline in older adults. J Alzheimers Dis. 2015; 44(4):1361-73.View Related Profiles.

Ruberg, Frederick
Gifford, Katherine

PMID: 25471188; PMCID: PMC4336578; DOI: 10.3233/JAD-141812;

Ahmadian A, Brogan A, Berman J, Sverdlov AL, Mercier G, Mazzini M, Govender P, Ruberg FL, Miller EJ. Quantitative interpretation of FDG PET/CT with myocardial perfusion imaging increases diagnostic information in the evaluation of cardiac sarcoidosis. J Nucl Cardiol. 2014 Oct; 21(5):925-39.View Related Profiles.

Sverdlov, Aaron
Miller, Edward
Ruberg, Frederick
Mercier, Gustavo
Berman, Jeffrey
Mazzini, Michael
Govender, Praveen

PMID: 24879453; DOI: 10.1007/s12350-014-9901-9;

Hua N, Chen Z, Phinikaridou A, Pham T, Qiao Y, LaValley MP, Bigornia SJ, Ruth MR, Apovian CM, Ruberg FL, Hamilton JA. The influence of pericardial fat upon left ventricular function in obese females: evidence of a site-specific effect. J Cardiovasc Magn Reson. 2014; 16:37.View Related Profiles.

Phinikaridou, Alkystis
Apovian, Caroline
Ruberg, Frederick
Hamilton, James
Ruth, Megan
LaValley, Michael
Hua, Ning

PMID: 24884541; PMCID: PMC4046092; DOI: 10.1186/1532-429X-16-37;

Berman JS, Govender P, Ruberg FL, Mazzini M, Miller EJ. Scadding revisited: a proposed staging system for cardiac sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 2014; 31(1):2-5.View Related Profiles.

Ruberg, Frederick
Berman, Jeffrey
Mazzini, Michael
Govender, Praveen

PMID: 24751447

Girnius S, Seldin DC, Meier-Ewert HK, Sloan JM, Quillen K, Ruberg FL, Berk JL, Doros G, Sanchorawala V. Safety and efficacy of high-dose melphalan and auto-SCT in patients with AL amyloidosis and cardiac involvement. Bone Marrow Transplant. 2014 Mar; 49(3):434-9.View Related Profiles.

Seldin, David
Ruberg, Frederick
Doros, Gheorghe
Meier-Ewert, Hans Kilian
Sloan, J.
Berk, John
Quillen, Karen
Sanchorawala, Vaishali

PMID: 24317129; DOI: 10.1038/bmt.2013.192;

Ruberg FL. T1 mapping in cardiac amyloidosis: can we get there from here? JACC Cardiovasc Imaging. 2013 Apr; 6(4):498-500. PMID: 23498671; DOI: 10.1016/j.jcmg.2013.01.007;

Ruberg FL, Miller EJ. Nuclear tracers for transthyretin cardiac amyloidosis: time to bone up? Circ Cardiovasc Imaging. 2013 Mar 1; 6(2):162-4.View Related Profiles.

Miller, Edward
Ruberg, Frederick

PMID: 23512778; DOI: 10.1161/CIRCIMAGING.113.000178;

Tsai SB, Seldin DC, Quillen K, Berk JL, Ruberg FL, Meier-Ewert H, Sloan JM, Doros G, Finn KT, Skinner M, Sanchorawala V. High-dose melphalan and stem cell transplantation for patients with AL amyloidosis: trends in treatment-related mortality over the past 17 years at a single referral center. Blood. 2012 Nov 22; 120(22):4445-6.View Related Profiles.

Seldin, David
Ruberg, Frederick
Doros, Gheorghe
Meier-Ewert, Hans Kilian
Sloan, J.
Berk, John
Quillen, Karen
Skinner, Martha
Sanchorawala, Vaishali

PMID: 23175664; DOI: 10.1182/blood-2012-09-457341;

Ruberg FL, Berk JL. Transthyretin (TTR) cardiac amyloidosis. Circulation. 2012 Sep 4; 126(10):1286-300.View Related Profiles.

Ruberg, Frederick
Berk, John

PMID: 22949539; PMCID: PMC3501197; DOI: 10.1161/CIRCULATIONAHA.111.078915;

Ruberg FL, Maurer MS, Judge DP, Zeldenrust S, Skinner M, Kim AY, Falk RH, Cheung KN, Patel AR, Pano A, Packman J, Grogan DR. Prospective evaluation of the morbidity and mortality of wild-type and V122I mutant transthyretin amyloid cardiomyopathy: the Transthyretin Amyloidosis Cardiac Study (TRACS). Am Heart J. 2012 Aug; 164(2):222-228.e1.View Related Profiles.

Ruberg, Frederick
Skinner, Martha

PMID: 22877808; DOI: 10.1016/j.ahj.2012.04.015;

Freeman B, Sloan JM, Seldin DC, Cowan AJ, Ruberg FL, Sanchorawala V. Multiple arterial and venous thromboembolic complications in AL amyloidosis and cardiac involvement: a case report and literature review. Amyloid. 2012 Sep; 19(3):156-60.View Related Profiles.

Seldin, David
Ruberg, Frederick
Sloan, J.
Sanchorawala, Vaishali

PMID: 22680044; DOI: 10.3109/13506129.2012.694825;

Meier-Ewert HK, Sanchorawala V, Berk JL, Ruberg FL. Cardiac amyloidosis: evolving approach to diagnosis and management. Curr Treat Options Cardiovasc Med. 2011 Dec; 13(6):528-42.View Related Profiles.

Ruberg, Frederick
Meier-Ewert, Hans Kilian
Berk, John
Sanchorawala, Vaishali

PMID: 21989745; DOI: 10.1007/s11936-011-0147-4;

Cibeira MT, Sanchorawala V, Seldin DC, Quillen K, Berk JL, Dember LM, Segal A, Ruberg F, Meier-Ewert H, Andrea NT, Sloan JM, Finn KT, Doros G, Blade J, Skinner M. Outcome of AL amyloidosis after high-dose melphalan and autologous stem cell transplantation: long-term results in a series of 421 patients. Blood. 2011 Oct 20; 118(16):4346-52.View Related Profiles.

Seldin, David
Ruberg, Frederick
Doros, Gheorghe
Meier-Ewert, Hans Kilian
Sloan, J.
Berk, John
Quillen, Karen
Dember, Laura
Skinner, Martha
Sanchorawala, Vaishali

PMID: 21828140; PMCID: PMC3204906; DOI: 10.1182/blood-2011-01-330738;

Seldin DC, Andrea N, Berenbaum I, Berk JL, Connors L, Dember LM, Doros G, Fennessey S, Finn K, Girnius S, Lerner A, Libbey C, Meier-Ewert HK, O'Connell R, O'Hara C, Quillen K, Ruberg FL, Sam F, Segal A, Shelton A, Skinner M, Sloan JM, Wiesman JF, Sanchorawala V. High-dose melphalan and autologous stem cell transplantation for AL amyloidosis: recent trends in treatment-related mortality and 1-year survival at a single institution. Amyloid. 2011 Jun; 18 Suppl 1:127-9.View Related Profiles.

Lerner, Adam
O'Hara, Carl
Libbey, Caryn
Seldin, David
Sam, Flora
Ruberg, Frederick
Doros, Gheorghe
Meier-Ewert, Hans Kilian
Berenbaum, Isidore
Sloan, J.
Wiesman, Janice
Berk, John
Quillen, Karen
Dember, Laura
Connors, Lawreen
Skinner, Martha
Sanchorawala, Vaishali

PMID: 21838459; PMCID: PMC5601311; DOI: 10.3109/13506129.2011.574354047;

Meier-Ewert HK, Sanchorawala V, Berk J, Finn KT, Skinner M, Seldin DC, Ruberg FL. Regression of cardiac wall thickness following chemotherapy and stem cell transplantation for light chain (AL) amyloidosis. Amyloid. 2011 Jun; 18 Suppl 1:130-1.View Related Profiles.

Seldin, David
Ruberg, Frederick
Meier-Ewert, Hans Kilian
Berk, John
Skinner, Martha
Sanchorawala, Vaishali

PMID: 21838460; DOI: 10.3109/13506129.2011.574354048;

Tsai SB, Seldin DC, Wu H, O'Hara C, Ruberg FL, Sanchorawala V. Myocardial infarction with "clean coronaries" caused by amyloid light-chain AL amyloidosis: a case report and literature review. Amyloid. 2011 Sep; 18(3):160-4.View Related Profiles.

O'Hara, Carl
Seldin, David
Ruberg, Frederick
Sanchorawala, Vaishali

PMID: 21504342; DOI: 10.3109/13506129.2011.571319;

Bhuiyan T, Helmke S, Patel AR, Ruberg FL, Packman J, Cheung K, Grogan D, Maurer MS. Pressure-volume relationships in patients with transthyretin (ATTR) cardiac amyloidosis secondary to V122I mutations and wild-type transthyretin: Transthyretin Cardiac Amyloid Study (TRACS). Circ Heart Fail. 2011 Mar; 4(2):121-8. PMID: 21191093; PMCID: PMC4939845; DOI: 10.1161/CIRCHEARTFAILURE.109.910455;

Ruberg FL. Paying at the pump: diet-induced accumulation of cardiac lipid and systolic dysfunction. Circ Cardiovasc Imaging. 2010 Nov; 3(6):635-7. PMID: 21081742; DOI: 10.1161/CIRCIMAGING.110.960476;

Amsterdam EA, Kirk JD, Bluemke DA, Diercks D, Farkouh ME, Garvey JL, Kontos MC, McCord J, Miller TD, Morise A, Newby LK, Ruberg FL, Scordo KA, Thompson PD. Testing of low-risk patients presenting to the emergency department with chest pain: a scientific statement from the American Heart Association. Circulation. 2010 Oct 26; 122(17):1756-76. PMID: 20660809; PMCID: PMC3044644; DOI: 10.1161/CIR.0b013e3181ec61df;

Phinikaridou A, Ruberg FL, Hallock KJ, Qiao Y, Hua N, Viereck J, Hamilton JA. In vivo detection of vulnerable atherosclerotic plaque by MRI in a rabbit model. Circ Cardiovasc Imaging. 2010 May; 3(3):323-32.View Related Profiles.

Phinikaridou, Alkystis
Ruberg, Frederick
Hamilton, James
Hallock, Kevin
Hua, Ning

PMID: 20194634; DOI: 10.1161/CIRCIMAGING.109.918524;

Ruberg FL, Chen Z, Hua N, Bigornia S, Guo Z, Hallock K, Jara H, LaValley M, Phinikaridou A, Qiao Y, Viereck J, Apovian CM, Hamilton JA. The relationship of ectopic lipid accumulation to cardiac and vascular function in obesity and metabolic syndrome. Obesity (Silver Spring). 2010 Jun; 18(6):1116-21.View Related Profiles.

Phinikaridou, Alkystis
Apovian, Caroline
Ruberg, Frederick
Jara, Hernan
Hamilton, James
Hallock, Kevin
LaValley, Michael
Hua, Ning
Chen, Zhongjing

PMID: 19875992; PMCID: PMC3264050; DOI: 10.1038/oby.2009.363;

Ruberg FL, Judge DP, Maurer MS. Familial amyloid cardiomyopathy due to TTR mutations: an underdiagnosed cause of restrictive cardiomyopathy [corrected]. J Card Fail. 2009 Jun; 15(5):464. PMID: 19477408; DOI: 10.1016/j.cardfail.2009.04.003;

Ruberg FL, Appelbaum E, Davidoff R, Ozonoff A, Kissinger KV, Harrigan C, Skinner M, Manning WJ. Diagnostic and prognostic utility of cardiovascular magnetic resonance imaging in light-chain cardiac amyloidosis. Am J Cardiol. 2009 Feb 15; 103(4):544-9.View Related Profiles.

Ozonoff, Alexander
Ruberg, Frederick
Skinner, Martha
Davidoff, Ravin

PMID: 19195518; PMCID: PMC2680134; DOI: 10.1016/j.amjcard.2008.09.105;

Goyal SK, Punnam SR, Verma G, Ruberg FL. Persistent left superior vena cava: a case report and review of literature. Cardiovasc Ultrasound. 2008; 6:50. PMID: 18847480; PMCID: PMC2576163; DOI: 10.1186/1476-7120-6-50;

Rosito GA, Massaro JM, Hoffmann U, Ruberg FL, Mahabadi AA, Vasan RS, O'Donnell CJ, Fox CS. Pericardial fat, visceral abdominal fat, cardiovascular disease risk factors, and vascular calcification in a community-based sample: the Framingham Heart Study. Circulation. 2008 Feb 5; 117(5):605-13.View Related Profiles.

O'Donnell, Christopher
Ruberg, Frederick
Massaro, Joseph
Ramachandran, Vasan

PMID: 18212276; DOI: 10.1161/CIRCULATIONAHA.107.743062;

Dinwoodey DL, Skinner M, Maron MS, Davidoff R, Ruberg FL. Light-chain amyloidosis with echocardiographic features of hypertrophic cardiomyopathy. Am J Cardiol. 2008 Mar 1; 101(5):674-6.View Related Profiles.

Ruberg, Frederick
Skinner, Martha
Davidoff, Ravin

PMID: 18308019; DOI: 10.1016/j.amjcard.2007.10.031;

Ruberg FL. Myocardial lipid accumulation in the diabetic heart. Circulation. 2007 Sep 4; 116(10):1110-2. PMID: 17768302

Qiao Y, Ronen I, Viereck J, Ruberg FL, Hamilton JA. Identification of atherosclerotic lipid deposits by diffusion-weighted imaging. Arterioscler Thromb Vasc Biol. 2007 Jun; 27(6):1440-6.View Related Profiles.

Ruberg, Frederick
Hamilton, James

PMID: 17379838; PMCID: PMC2910580; DOI: 10.1161/ATVBAHA.107.141028;

Ruberg FL, McDonnell ME, Trabb J, Shemin RJ, Hoyt RF, Braverman LE, Balady GJ. An intracardiac accessory thyroid gland. Am J Cardiol. 2006 Mar 15; 97(6):926-8.View Related Profiles.

Ruberg, Frederick
Balady, Gary
Braverman, Lewis
McDonnell, Marie
Hoyt, Richard

PMID: 16516604

Ruberg FL, Loscalzo J. Normal Mechanisms of Hemostasis. In: Loscalzo J, Dzau V, and Creager M, eds. Vascular Medicine, A Companion to Braunwald’s Heart Disease. Saunders/Elsevier. Philadelphia. 2006; 61-70.

Davidoff R, Ruberg FL. Newer cardiac imaging techniques: multidetector CT angiography. J Insur Med. 2006; 38(2):116-25.View Related Profiles.

Ruberg, Frederick
Davidoff, Ravin

PMID: 16845845

Ruberg FL, Viereck J, Phinikaridou A, Qiao Y, Loscalzo J, Hamilton JA. Identification of cholesteryl esters in human carotid atherosclerosis by ex vivo image-guided proton MRS. J Lipid Res. 2006 Feb; 47(2):310-7.View Related Profiles.

Phinikaridou, Alkystis
Ruberg, Frederick
Hamilton, James

PMID: 16317172

Ruberg FL, Kissinger KV, Manning WJ. Images in cardiovascular medicine. Diaphragmatic motion during Cheyne-Stokes respiration by navigator magnetic resonance imaging. Circulation. 2005 Sep 6; 112(10):e132. PMID: 16145007

Viereck J, Ruberg FL, Qiao Y, Perez AS, Detwiller K, Johnstone M, Hamilton JA. MRI of atherothrombosis associated with plaque rupture. Arterioscler Thromb Vasc Biol. 2005 Jan; 25(1):240-5.View Related Profiles.

Ruberg, Frederick
Hamilton, James

PMID: 15528478

Ruberg FL, Leopold JA, Loscalzo J. Atherothrombosis: plaque instability and thrombogenesis. Prog Cardiovasc Dis. 2002 Mar-Apr; 44(5):381-94. PMID: 12024336

Ruberg FL, Loscalzo J. Prothrombotic determinants of coronary atherothrombosis. Vasc Med. 2002; 7(4):289-99. PMID: 12710845

O'Brien CD, Ji G, Wang YX, Sun J, Krymskaya VP, Ruberg FL, Kotlikoff MI, Albelda SM. PECAM-1 (CD31) engagement activates a phosphoinositide-independent, nonspecific cation channel in endothelial cells. FASEB J. 2001 May; 15(7):1257-60. PMID: 11344106

Gurubhagavatula I, Amrani Y, Pratico D, Ruberg FL, Albelda SM, Panettieri RA. Engagement of human PECAM-1 (CD31) on human endothelial cells increases intracellular calcium ion concentration and stimulates prostacyclin release. J Clin Invest. 1998 Jan 1; 101(1):212-22. PMID: 9421484; PMCID: PMC508558

Ruberg FL, Skene DJ, Hanifin JP, Rollag MD, English J, Arendt J, Brainard GC. Melatonin regulation in humans with color vision deficiencies. J Clin Endocrinol Metab. 1996 Aug; 81(8):2980-5. PMID: 8768862

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 109 publications over 23 distinct years, with a maximum of 11 publications in 2017 and 2019

Bar chart showing 109 publications over 23 distinct years, with a maximum of 11 publications in 2017 and 2019

Year	Publications
1996	1
1998	1
2001	1
2002	2
2004	1
2005	2
2006	3
2007	3
2008	3
2009	2
2010	4
2011	5
2012	4
2013	3
2014	3
2015	5
2016	6
2017	11
2018	9
2019	11
2020	9
2021	10
2022	10

Media Mentions

Heart Failure Imaging: Where Are We Now?

Medscape 1/7/2022

Study aims to achieve earlier diagnosis of ATTR cardiac amyloidosis in minority populations

News Medical 9/4/2019

Cardiac Transthyretin Amyloidosis Often Diagnosed Late

MD Alert/Reuters 6/4/2019

Carpal Tunnel Surgery a Chance to Catch Amyloid Heart Disease

MedPage Today 10/15/2018

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

amyloidosis
Cardiac-Gated Imaging Techniques
echocardiography
MRI

Dr. Ruberg is Associate Chief of Cardiovascular Medicine for Academic Affairs and Director, Pilot Grants Program, BU Clinical and Translational Science Program. He is Associate Professor of Medicine and Radiology at Boston University School of Medicine. Dr. Ruberg is also Associate Program Director of the Cardiovascular Medicine Fellowship Training Program. An active clinical cardiologist and clinical investigator, Dr. Ruberg’s commitment to interdisciplinary research and team science is exemplified by his various responsibilities at BUMC. He is the Director of the Advanced Cardiac Imaging Program at Boston Medical Center – a clinical service involving clinicians and trainees in the Departments of Radiology and Medicine. His clinical interest is in infiltrative cardiomyopathy and he is a participating clinician and researcher in the multi-disciplinary BU/BMC Amyloidosis Center and Sarcoidosis Center. He is an internationally recognized expert in cardiac amyloidosis. His clinical and research expertise is in the field of cardiac imaging with interest in refining quantitative techniques for application in the clinical care of infiltrative cardiomyopathies. His research has been funded by the American Heart Association (AHA), Amyloidosis Foundation, industry, and NIH. Research collaboration include investigators in Boston, elsewhere in the US, and world-wide. Dr. Ruberg has served as Associate Editor of Circulation: Cardiovascular Imaging since 2016. He is a fellow of the American College of Cardiology and the American Heart Association. Dr. Ruberg is an active mentor of Internal Medicine residents and Cardiovascular Medicine fellows, having been awarding the 2017 Research Mentor of the year award from the IM residency. He serves on the Executive Committee of the newly funded NIH/NHLBI R38 award (Vasan Ramchandran, MD, PI) research in residency/StARR designed to facilitate research experiences for MD-trained IM residents.

Available to Mentor as: (Review Mentor Role Definitions):