TNF-Alpha

Tumor necrosis factor alpha (TNF-α) is a proinflammatory cytokine that is used as a marker of Inflammation. Its reduction is thought to reflect a lesser state of inflammation in the body.

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Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect tnf-alpha

Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
Fish Oil
All comparative evidence is now gathered in our ​Supplement Goals Reference.
The evidence for each separate supplement is still freely available ​here.
Conjugated Linoleic Acid  
Ganoderma lucidum  
Garlic  
Japanese Knotweed  
Resveratrol  
Tetradecyl Thioacetic Acid  
Vitamin D  
Zinc  
Blueberry  
Cocoa Extract  
Colostrum  
Creatine  
L-Carnitine  
Lactobacillus reuteri  
Punicic Acid  
Rose Hip  
Stinging Nettle  
Trimethylglycine  
Vitamin B3  
Vitamin E  
Perilla Oil