Lactate Production

Lactate can be produced during prolonged exercise, and while it is not thought to contribute to muscular failure it seems to be a good biomarker of it. Reductions in lactate production tend to be associated with prolonged physical endurance.

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Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect lactate production

Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
Sodium Bicarbonate
All comparative evidence is now gathered in our ​Supplement Goals Reference.
The evidence for each separate supplement is still freely available ​here.
Caffeine  
L-Carnitine  
Branched Chain Amino Acids  
Panax ginseng  
Rhodiola Rosea  
Arginine  
Citrulline  
Phosphatidylserine