IGF-1

Insulin-like growth factor-1 (IGF-1) is an anabolic derivative of Growth Hormone that is thought to mediate cell growth and muscle protein synthesis. Supplements that increase IGF-1 are thought to promote muscle hypertrophy.

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Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect igf-1

Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
Dehydroepiandrosterone
All comparative evidence is now gathered in our ​Supplement Goals Reference.
The evidence for each separate supplement is still freely available ​here.
Zinc  
Colostrum  
Creatine  
Red Clover Extract  
Trimethylglycine  
Ursolic Acid  
Citrulline  
Eurycoma Longifolia Jack  
HMB  
L-Carnitine  
Melatonin  
Olive leaf extract  
Velvet Antler  
Whey Protein