ಮಾಧ್ಯಮ
- ಟ್ವೀಟ್ಗಳು
- ಟ್ವೀಟ್ಗಳು & ಪ್ರತಿಕ್ರಿಯೆಗಳು
- ಮಾಧ್ಯಮ, ಪ್ರಸ್ತುತ ಪುಟ.
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Exploration of the cattle rumen microbiome with PacBio, Illumina, and Hi-C. Comparison of the techs and assignment of virus and antimicrobial resistance genes to microbial hosts. New work w/ Derek Bickhart
@BioMickWatson@sergekoren &@tplsmith https://www.biorxiv.org/content/early/2018/12/09/491175 …pic.twitter.com/XMWfSPfgA3
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"Improved reference genome of Aedes aegypti informs arbovirus vector control" The project that put genome assembly to the front page of the
@nytimes is finally published! Loved working with@pollyp1 et al. Link to paper: http://rdcu.be/bboo6 And a bonus pic of Ben Matthews :)pic.twitter.com/BTuEhsMOVG
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My academic brother
@mike_schatz introducing our shared (and exemplary) PhD advisor@StevenSalzberg1 at#biodata2018pic.twitter.com/PL7vo22fhR
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Great idea from
@traingene and@dnasko to look at all past RefSeq versions and show how Kraken classifications depend heavily on the database. Our new paper: https://genomebiology.biomedcentral.com/articles/10.1186/s13059-018-1554-6 …pic.twitter.com/5PYAQSeGPq
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We thought 20 Mbp haplotigs were pretty incredible when we first wrote the trio binning paper. Since then, we've assembled 70 Mbp(!!) NG50 haplotigs for
@tplsmith's latest cross between a Highland bull and a yakpic.twitter.com/nWzNmLnM85
ಈ ಥ್ರೆಡ್ ತೋರಿಸಿ -
"De novo assembly of haplotype-resolved genomes with trio binning" now out in
@NatureBiotech! With@sergekoren@ArangRhie@AlexDilthey@drsarahdoom@tplsmith Link: https://rdcu.be/9Pi4 pic.twitter.com/dMxcPi0nWZ
ಈ ಥ್ರೆಡ್ ತೋರಿಸಿ -
Congrats to Dr.
@jayghurye on his successful defense!
pic.twitter.com/SWB0IO64t5
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Goldfish genome! "De Novo assembly of the goldfish (Carassius auratus) genome and the evolution of genes after whole genome duplication" from
@SMBurgessLab and co. https://www.biorxiv.org/content/early/2018/07/20/373431 …pic.twitter.com/u3aTNqtJfI
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Want to quickly map your long-read metagenome against all RefSeq and estimate sample composition? Our new preprint with
@AlexDilthey shows you how: "MetaMaps - Strain-level metagenomic assignment and compositional estimation for long reads" https://www.biorxiv.org/content/early/2018/07/20/372474 …pic.twitter.com/QBU4zCrYgM
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The human rDNA unit makes for a pretty dotplot. There are hundreds of these per genome and accurately assembling them is one of the last remaining challenges of the human genome.
@PacBio and@nanopore now give us a fighting chance.pic.twitter.com/viFjdQW04W
ಈ ಥ್ರೆಡ್ ತೋರಿಸಿ -
"RefSeq database growth influences the accuracy of k-mer-based species identification" https://www.biorxiv.org/content/early/2018/04/19/304972 … A shame that
@traingene didn't go with my suggested title "No, that's not actually anthrax on the subway, international space station, etc."pic.twitter.com/EHJ7FLu2zj
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I'm not saying
@BioMickWatson is wrong, I'm just saying if you look at all microbial genomes in RefSeq the difference in % frameshifted genes between PacBio and Illumina assemblies is quite small. IonTorrent on the other hand... (Plot via@sergekoren)pic.twitter.com/lzUVTokzR8
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KAT is a great way to evaluate an assembly, and was very helpful for this project. The supplement is full of KAT plots, like this pretty one from an A. thaliana cross. Thank you
@bjclavijo an co!pic.twitter.com/AgCMBDVu5R
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"Complete assembly of parental haplotypes with trio binning" My favorite kind of method -- simple to explain, works brilliantly.
@sergekoren@ArangRhie@tplsmith et al. launch the#20MbHaplotigClub https://www.biorxiv.org/content/early/2018/02/26/271486 …pic.twitter.com/SwXVo4hoyh
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Fast approximate algorithms like MashMap let you do previously impractical things like an all-pairs comparison of every known microbial genome (e.g. https://www.biorxiv.org/content/early/2017/11/27/225342 … also from
@chirgjain)pic.twitter.com/T2fSnDr3DY
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Our latest with
@chirgjain "A Fast Adaptive Algorithm for Computing Whole-Genome Homology Maps" (https://www.biorxiv.org/content/early/2018/02/05/259986 …) used to make this nifty image of all human repeats >85% identity (blue 1-5 kb, red 5-10 kb, black >10 kb)pic.twitter.com/ph1Dy6IUXk
ಈ ಥ್ರೆಡ್ ತೋರಿಸಿ -
No joke. That's essentially what we did with
@tplsmith and friends and it worked amazingly well. Tim wants to do a liger next ;)pic.twitter.com/2yCmjKdyeS
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Dimensions of a sequencing nanopore and 1 Mbp strand of DNApic.twitter.com/zjxTF3wHXd
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