Phusion Passenger is one of the easiest ways to build a production-ready deployment of Ruby applications with NGINX.
Using one of the many other Ruby on Rails frameworks (for example, Thin and Unicorn), you can use NGINX as a front-end proxy to offload HTTP optimizations, SSL, and static content.
PHP-FPM is a process manager for PHP, and one of the most common ways to deploy NGINX and PHP together.
The uWSGI interface is most common way to run Python applications with NGINX.