Calgary Depression Scale for Schizophrenia, in Arabic

Scientists from Qatar and the United States have managed to validate an Arabic version of the Calgary Depression Scale for Schizophrenia (CDSS) among patients with schizophrenia.

Schizophrenics commonly show both depressive and negative symptoms that can affect the prognosis and course of their treatment. Negative symptoms are disabling symptoms that have a major impact on the quality of life of patients, more so than positive symptoms, which are thought patterns and behaviors that patients acquire after they become ill.

Tests such as CDSS are designed to distinguish between depression, and negative symptoms that are distinctive of schizophrenia.

These tests are not diagnostic per se, “but they are mainly there to asses the severity of psychotic symptoms in schizophrenia and the possible associated depressive symptoms (using CDSS),” explains Hassen Al-Amin, professor of psychiatry at Weill Cornell Medicine-Qatar and corresponding author of the study that validated the psychiatric test.

“They are significant because they can help us know how sick these patients are and also to monitor how they are responding to treatment with time,” he says.

These types of tests have been used worldwide and their validity is established.

In order to make them work for Arab populations, experts and researchers had to translate the material thoroughly and decide the appropriate cultural equivalents in Arabic. “We then test the Arabic versions with Arab patients with schizophrenia and compare them with those obtained internationally to make sure that we have a valid scale that is culturally acceptable also,” says Al-Amin.

Reactions: Javier Pérez-Ramírez

513_223x273_1_1_0Javier Pérez-Ramírez is a Full Professor in the Department of Chemistry and Applied Biosciences at ETH Zurich, and works on the design of catalytic materials and reactor concepts for the production of chemicals and fuels, with emphasis on sustainability and resource efficiency. His group published “Catalyst design for natural-gas upgrading through oxybromination chemistry” in Nature Chemistry earlier this year.

1. What made you want to be a chemical engineer?

My passion throughout my youth was playing tennis, which I hoped to make a career. This did not work for various reasons, prompting a change in direction to attend university. The choice of chemical engineering was somewhat improvised, since I hadn’t considered an academic path, but after the first semester I was really attracted to chemical processes, a flame which still burns today.

2. If you weren’t a chemist and could do any other job, what would it be — and why?

I could commit to any activity driven by a strong dose of creativity, like any expression of art.

3. What are you working on now, and where do you hope it will lead?

We are interested in the discovery, understanding, and implementation of catalytic processes devoted to sustainable technologies. The latter secure the efficient utilization of natural resources, the transition to renewable feedstocks, reduced energy consumption and waste, and minimized environmental impact. More specifically, we target the design of practically relevant catalysts for natural gas functionalization, carbon dioxide valorization, the conversion of biomass to chemicals and fuels, and novel manufacturing approaches to specialty chemicals.

4. Which historical figure would you most like to have dinner with — and why?

I would meet with John Hutchinson, John McClelland, William Gossage, Holbrook Gaskell, and Henry Deacon at the time they conceived the modern chemical industry in Widnes, England.

5. When was the last time you did an experiment in the lab — and what was it?

I am still experimentally active and master the process of coffee making every day; this is done in a highly reproducible way.

6. If exiled on a desert island, what one book and one music album would you take with you?

Given the remote setting, I would take a thick notebook to write and draw. As for a music album, if Spotify is out of the question I would face the dilemma between The Bootleg Series Volumes 1-3 or The Ties that Bind: The River Collection. I need more time to think…

7. Which chemist would you like to see interviewed on Reactions — and why?

I would be curious to read the answers of my colleague and friend Núria López.

First Rounders: Nancy J Kelley

Nancy J. Kelley

Nancy J. Kelley

Click here for the First Rounders podcast with Nancy Kelley. For more on her consultancy, go here. A Frontline interview with Nancy’s college friend (and Black Panther Party member) Kathleen Cleaver can be read here. A New York Times blog post on the East River Science Park’s first tenant is here. We published an article on the New York Genome Center, and Nancy, here. And here is a BuzzFeed article on the Genome Project-Write (side note: the author of that article, Nidhi Subbaraman, was once a Nature Biotech intern). The Science paper on Genome Project-Write is here.

Brady Huggett

 

 

The rise and fall of the UFO

Posted on behalf of Daniel Cressey

ARC028 - UFO - CoverIt seems amazing that anyone ever believed in them. In the mid-twentieth-century heyday of unidentified flying objects (UFOs), grainy pictures of flying saucers hovering in the sky were a staple even in  respectable magazines such as Time and Life. Volumes were written earnestly detailing the visits of aliens. This novel form of cold war paranoia seemed to seep into the collective psyche on both sides of the Atlantic.

For believe they did. A sizeable section of the public ate up cheap books on saucers and devoured tales of visitors from beyond our planet, whether their intent was good or ill. Fortunately for anyone enamoured of American subcultures in all their garish glory, the speculative-fiction writer Jack Womack has amassed a huge collection of these books, from sex-obsessed adult novels to earnest pseudo-academic treatises. He reproduces many of these gems in his lavishly illustrated menagerie of the tracts, Flying Saucers Are Real.

ARC028 - UFO - MIichael, C - Round Trip To Hell In A Flying Saucer

A 1955 title.

They range from what Womack calls the “finest science fiction cover to ever appear on a non-science fiction book” (The Flying Saucers Are Real by Donald Keyhoe) to the mundane (Richard S. Shaver’s 1948 I Remember Lemuria).

While Womack is deeply invested in these books, he doesn’t spare them. UFO Photographs Around the World Vols 1 and 2, he notes, “offers the most complete compilation of lens flares, camera smudges, film imperfections, blurs and jiggled shots ever published”. Womack points out that British linguist Gavin Gibbons (author of The Coming of the Space Ships (1956) and They Rode In Space Ships (1957)), and others from the UK brought “a wide-eyed if not overly creative spirit to the field”. Gibbons rewrote other people’s UFO encounters, “managing to make their accounts far less interesting”.

This is no attempt to deconstruct the reasons behind the rise and fall of the UFO. Instead, Womack seems to be attempting to understand a bizarre lost cult by collecting the artefacts they left.

We learn of George Adamski, born in Poland in 1891, who ended up founding the “Royal Order of Tibet” in California (and co-writing the 1953 Flying Saucers Have Landed) before setting up an eatery. Adamski’s ‘close encounters’ include a man who claimed to be from Venus — evidenced by the fact that his “trousers were not like mine”. In Britain, Leonard G. Cramp’s 1966 UFOs and Anti-Gravity purported to lay bare the engineering of the flying saucer, complete with detailed blueprints, which he apparently thought revealed an anti-gravity system “similar to one of his own devising”.

Womack describes another book, Flying Saucer from Mars (1954), as written by “Cedric Allingham” — a hoax said to have been perpetrated by a now-deceased British astronomer and his friend. This friend apparently admitted pretending to be Allingham to give a talk to a flying saucer club, during which he wore a false moustache.

Harold T. Wilkins's 1954 text.

Harold T. Wilkins’s 1954 text.

Womack’s book can be as confusing to follow as the arguments of his UFO proponents. The typefaces switch to signal passages from source materials, and covers, photos and drawings abound. Following the huge numbers of authors mentioned and whether they are believers, hoaxers or fictional becomes something of a task. There is no clear logic to this collection of what science-fiction luminary William Gibson calls “testimonials to certain human needs” in the introduction.

Some of the notes accompanying the awesome images are brief and baffling. We read on page 10: “When John C. Sherwood was seventeen, Gray Barker published his book, Flying Saucers are Watching You (1967), a dry account of events during the 1966 Michigan Flap. Barker’s congratulation, post-publication, ‘Evidently the fans swallowed this one with a gulp.’” Who Sherwood and Barker are, and what the “Michigan Flap” was, we can only guess.

Womack’s collection is heading to Georgetown University Library in Washington DC, to be preserved among its special collections. It may stand as a monument to collective lunacy, a testament to how easily people can be led down the garden path, or simply a collection of egregious publishing mistakes. Whichever it is, Womack has preserved a record of something that felt very real to a great many people. These books began emerging, after all, around a decade after the filmmaker and theatre impresario Orson Welles inadvertently frightened an estimated 1.2 million US listeners during his famous 1938 radio broadcast of an adaption of H.G. Wells’s The War of the Worlds.

Today, the ubiquitous advanced cameras mean the lack of convincing photographs is more and more of a problem for believers. The evidence collected here is as ‘real’ as flying saucers will ever get.

Daniel Cressey is a senior reporter for Nature in London. He tweets at @dpcressey. Flying Saucers Are Real is the first book release of New York City publisher Anthology Editions, a partnership between Boo-Hooray Gallery and Anthology Recordings.

 

For Nature’s full coverage of science in culture, visit www.nature.com/news/booksandarts.