Co-Design Project 3 -
Multi-Level Human Brain Atlas

The overall aim of Co-Design Project 3 is to develop a prototype of a comprehensive multimodal and multi-scale human brain atlas.

To support this, CDP3 will develop eight Products, which depend on components in several Tasks in different Subprojects. Most of the Products depend on a mixture of Tasks in several Subprojects, including SP2 (Strategic Human Brain Data), SP4 (Theoretical Neuroscience), SP5 (Neuroinformatics), SP7 (High Performance Analytics and Computing), SP8 (Medical Informatics) and SP12 (Ethics and Society). Since all of the CDPs focus on developing relevant and usable parts of the overall infrastructure that are highly scientifically relevant within the scope of SGA1, prioritisation and selection of the initial Atlas Products is required. The initial work of CDP3 in SGA1 will be the construction of a topographical representation of the human brain on different scales and considering different aspects, followed by a comprehensive semantic representation in future SGAs. The selection of Products under SGA1 is based on the following principles:

• Products with a clearly defined use case, with practical relevance beyond the HBP
• Data sets to finalise the Product must be available in 2015, so that subsequent work in SGA1 can focus on integration of the data into the Neuroinformatics Platform
• Products should be based on 2D or 3D image data sets that could be topographically integrated into an agreed template.

The CDP3 Products to be developed are as follows:

• CDP3-P1: 2D interactive filmstrip viewer
• CDP3-P2: 3D interactive big data viewer
• CDP3-P3: Initial set of linked template data sets with labelled parcellations
• CDP3-P4: Initial qualitative and quantitative data sets
• CDP3-P5: Alignment tools for incoming data
• CDP3-P6: Initial set of interactive tools
• CDP3-P7: Realignment of knowledge graph for inter-subject variability
• CDP3-P8: Modelling and model validation using quantitative data