Lior Pachter

@lpachter

Bren Professor of Computational Biology at Caltech. Blog at .

Pasadena, CA
pachterlab.github.io
Se unió en abril de 2009
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  1. retwitteó
    19 dic.

    So why is this result nifty? (1/N)

    The ultra-diffuse galaxy NGC 1052-DF2 with MUSE: I. Kinematics of the stellar body [GA]
    2 respuestas 22 retweets 62 Me gusta
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  2. retwitteó
    hace 20 horas

    Our Cell Hashing work w/ is out ! Check out a few awesome experimental approaches for scRNA-seq multiplexing: - () - (Gartner Lab) - () -

    1 respuesta 71 retweets 150 Me gusta
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  3. retwitteó
    18 dic.

    With the recent onslaught of posts about the randomness and capricious nature of NIH reviews, I'd like to make a few statements. I agree that the review process is far from optimal, but I do not think it is the random process that many seem to believe:

    2 respuestas 20 retweets 37 Me gusta
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  4. 18 dic.

    How to write a paper in four minutes

    6 respuestas 127 retweets 283 Me gusta
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  5. 18 dic.

    An interesting single-cell study of X-inactivation focusing on the identification of escapees via allele-specific expression analysis.

    11 retweets 25 Me gusta
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  6. retwitteó
    18 dic.

    Whole blood transcriptome analysis in bipolar disorder reveals strong lithium effect

    7 retweets 15 Me gusta
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  7. retwitteó
    15 dic.

    I've always joked that, if my husband and I were hit by a bus, the headline would read "Google Engineer and woman hit by a bus." Except it's not funny because it's true

    Smithsonian names woman to top post at American History Museum
    24 respuestas 297 retweets 1.213 Me gusta
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  8. retwitteó
    10 dic.

    New preprint from our group. Personal favourite from my upcoming thesis.

    6 retweets 9 Me gusta
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  9. 16 dic.

    Design elements reflecting the importance of... chalk. An article on the Roland and Maxine Hall of Mathematics and Physics

    4 retweets 6 Me gusta
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  10. 16 dic.

    This .txt -> .xls -> .m gymnastics is ridiculous but interestingly is more popular as a language for single-cell genomics analysis than C/C++. See , and :

    2 respuestas 5 retweets 23 Me gusta
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  11. 16 dic.

    Running the demo code for this paper requires (1) downloading a large text file. Then (2) loading it in so it can be saved as a .xls file so that (3) a program provided by the authors can parse the .xls file.

    8 respuestas 16 retweets 53 Me gusta
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  12. retwitteó
    14 dic.

    "goes to show the divide between the way universities market the advancement of women in STEM to the public, compared to the actual experiences of women in these fields." I'm not going to disagree.

    1 respuesta 2 retweets 6 Me gusta
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  13. retwitteó
    14 dic.

    Probably not a good idea to impute single cell RNA-seq data... neuron-specific marker VGlut2/Slc17a6 is expressed at low levels in every single CNS cell cluster after SAVER imputation

    5 respuestas 15 retweets 41 Me gusta
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  14. 14 dic.

    Interesting paper focusing on extensive splicing dysregulation evident in RNA-seq from post-mortem brains of individuals with psychiatric disorders.

    14 retweets 34 Me gusta
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  15. retwitteó
    13 dic.

    Completely missed that our paper came out! TL;DR: Computational efficiency gains from kallisto paired with high concordance to traditional methods = no brainer: use pseudo-alignment/quasi-mapping.

    A comparison of RSEM and kallisto for reproducible cancer RNA-seq analysis with workflow design details by and .
    4 retweets 17 Me gusta
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  16. retwitteó
    25 ago. 2015

    “Do the best experiments you can, and always tell the truth. That’s all.” - Sydney Brenner. HT

    16 retweets 21 Me gusta
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  17. retwitteó
    11 dic.

    Gene expression during was amazingly stable despite huge changes in the . We tested wheat-rye hybrids, and Ph1 mutants and were surprised how little changed! Great collaboration with

    9 retweets 30 Me gusta
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  18. retwitteó
    6 ago.

    Differential gene expression analysis tools exhibit substandard performance for long non-coding RNA-sequencing data

    4 retweets 13 Me gusta
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  19. retwitteó
    9 dic.

    Some thoughts on ’s entry in , after being there and chatting with the AlphaFold team and many others: . Warning: long, technical (in parts), and vicious! (but not toward DM :-)

    15 respuestas 236 retweets 500 Me gusta
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  20. retwitteó
    9 dic.

    Rachel Posner, a rabbi's wife, captured this historic image in 1932 in Kiel, Germany, on the 8th night of Chanukah. On the back of the photograph, she wrote: "Death to Judah," so the flag says. "Judah will live forever," so the light answers.

    6 respuestas 267 retweets 653 Me gusta
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