Evolutionary interplay

Latest research

1. 1. Neuroscience

   Geometry and dynamics of representations in a precisely balanced memory network related to olfactory cortex

   Claire Meissner-Bernard, Friedemann Zenke, Rainer W Friedrich
2. 1. Cell Biology
   2. Genetics and Genomics

   DNA replication in primary hepatocytes without the six-subunit ORC

   Róża K Przanowska, Yuechuan Chen ... Anindya Dutta
3. 1. Microbiology and Infectious Disease

   Screening Envelope Genes Across Primate Genomes Reveals Evolution and Diversity Patterns of Endogenous Retroviruses

   Saili Chabukswar, Nicole Grandi ... Enzo Tramontano
4. 1. Neuroscience

   Compressed sensing based approach identifies modular neural circuitry driving learned pathogen avoidance

   Timothy Hallacy, Abdullah Yonar ... Sharad Ramanathan
5. 1. Immunology and Inflammation

   Downregulation of semaphorin 4A in keratinocytes reflects the features of non-lesional psoriasis

   Miki Kume, Hanako Koguchi-Yoshioka ... Rei Watanabe

   Downregulation of Sema4A in keratinocytes induces psoriatic non-lesional features, with its signaling cascades potentially triggering psoriasis and serving as targets for treatment and prevention.
6. 1. Structural Biology and Molecular Biophysics

   The known unknowns of the Hsp90 chaperone

   Laura-Marie Silbermann, Benjamin Vermeer ... Katarzyna Tych

   An exploration of the unanswered questions in how the molecular chaperone Hsp90 supports protein homeostasis, and how single-molecule techniques could drive future breakthroughs in answering them.
7. 1. Immunology and Inflammation
   2. Medicine

   JAK inhibition decreases the autoimmune burden in Down syndrome

   Angela L Rachubinski, Elizabeth Wallace ... Joaquín M Espinosa

   Treatment with a JAK inhibitor normalizes multiple biomarkers of autoinflammation and provides therapeutic benefit for diverse immune skin conditions in individuals with Down syndrome.
8. 1. Biochemistry and Chemical Biology
   2. Structural Biology and Molecular Biophysics

   Electrostatics of Salt-Dependent Reentrant Phase Behaviors Highlights Diverse Roles of ATP in Biomolecular Condensates

   Yi-Hsuan Lin, Tae Hun Kim ... Hue Sun Chan
9. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   The fate of pyruvate dictates cell growth by modulating cellular redox potential

   Ashish G Toshniwal, Geanette Lam ... Jared Rutter
10. 1. Biochemistry and Chemical Biology

    Synergistic effect of inhibiting CHK2 and DNA replication on cancer cell growth

    Flavie Coquel, Sing-Zong Ho ... Philippe Pasero