Since its inception in 1912, Isis has featured scholarly articles, research notes and commentary on the history of science, medicine, and technology, and their cultural influences. Review essays and book reviews on new publications in the field are also included. An official publication of the History of Science Society, this is the oldest (and most widely circulating) English-language journal in the field.

With a new Editor and editorial office in the Netherlands, the Press would like to acknowledge the following supporters: Ammodo Foundation; Descartes Centre, Utrecht University; Faculty of Humanities, Utrecht University; Huygens Institute for the History of the Netherlands; Museum Boerhaave, Dutch National Museum for the History of Science and Medicine.

Subscriptions to Isis are concurrent with membership in the History of Science Society. All individual and student subscribers are automatically enrolled as HSS members, with all attendant benefits.